Kubota Y, Inagaki S, Kito S, Shimada S, Okayama T, Hatanaka H, Pelletier G, Takagi H, Tohyama M
Department of Anatomy II, Osaka University Medical School, Japan.
Brain Res. 1988 Aug 23;458(2):389-93. doi: 10.1016/0006-8993(88)90484-2.
Double immunocytochemistry using peroxidase-antiperoxidase and protein A-gold was performed to determine whether neuropeptide Y (NPY) immunoreactive neurons receive synaptic inputs from catecholaminergic axon terminals in the rat neostriatum. Tyrosine hydroxylase-immunoreactive axons were found to be in synaptic contact with the somas and proximal dendrites of NPY-immunoreactive neostriatal neurons. These latter neurons were medium-sized and had indented nuclei, and thus were thought to be medium aspiny interneurons. Thus nigrostriatal dopaminergic neurons may monosynaptically influence striatal NPY neurons.
