Kubota Y, Inagaki S, Shimada S, Kito S, Eckenstein F, Tohyama M
Brain Res. 1987 Jun 9;413(1):179-84. doi: 10.1016/0006-8993(87)90167-3.
We used an electron microscopic 'mirror technique' to determine whether cholinergic neurons are in direct synaptic contact with dopaminergic axons in the rat neostriatum. Tyrosine hydroxylase-immunoreactive axons make synaptic contacts with the somata and proximal dendrites of large choline acetyltransferase-immunoreactive striatal neurons which are thought to be interneurons. This provides morphological evidence that nigrostriatal dopaminergic neurons can influence monosynaptically the striatal cholinergic neurons.
