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一种便携式精密电离室:传输电离参考室。

A portable precision ionization chamber: The transfer ionization reference chamber.

作者信息

Juget Frédéric, Nedjadi Youcef, Buchillier Thierry, Durán Teresa, Bochud François, Kottler Christian, Bailat Claude

机构信息

Institute of Radiation Physics, Grand Pré 1, 1007 Lausanne, Switzerland.

Institute of Radiation Physics, Grand Pré 1, 1007 Lausanne, Switzerland.

出版信息

Appl Radiat Isot. 2018 Apr;134:95-99. doi: 10.1016/j.apradiso.2017.10.022. Epub 2017 Oct 12.

DOI:10.1016/j.apradiso.2017.10.022
PMID:29054450
Abstract

A portable instrument was developed at the Institute of Radiation Physics (IRA) for on-site radionuclides measurements. It will enable the measurement of short-lived radionuclides in nuclear medicine departments or isotope production centres. The system involves an ionization chamber read directly by an electrometer and it was optimized to ensure a good reproducibility through the selection of an appropriate vial, filling volume and source position in the well chamber, as well as monitoring the external background and performing a detailed uncertainty estimation. The calibration factors were determined using solutions whose activity concentration is traceable to the international reference system using the IRA reference chamber. Currently the transfer ionization chamber is calibrated for F-18, C-11, O-15, N-13, I-131 and Tc-99m. The final instrument is able to measure isotope activities with a relative standard uncertainty not larger than 1%.

摘要

辐射物理研究所(IRA)开发了一种用于现场放射性核素测量的便携式仪器。它能够在核医学科室或同位素生产中心测量短寿命放射性核素。该系统包括一个由静电计直接读取的电离室,并通过选择合适的样品瓶、填充体积和井型电离室中的源位置进行了优化,以确保良好的重现性,同时监测外部本底并进行详细的不确定度估计。校准因子使用其活度浓度可溯源至国际参考系统的溶液,通过IRA参考电离室确定。目前,该转移电离室已针对F-18、C-11、O-15、N-13、I-131和Tc-99m进行了校准。最终仪器能够测量相对标准不确定度不大于1%的同位素活度。

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Molecules. 2023 Jan 31;28(3):1345. doi: 10.3390/molecules28031345.
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EJNMMI Phys. 2022 Mar 14;9(1):19. doi: 10.1186/s40658-022-00448-0.