Monges G, Treffot M J, Callier D, Devictor B, Casanova P, Hassoun J
Laboratoire d'Anatomie Pathologique et Neuropathologie, Faculté de Médecine Timone, Marseille.
Ann Pathol. 1988;8(4-5):290-4.
The number of gastrin cells (G cells) and somatostatin cells (D cells) per surface unit, and the G/D cell ratio were estimated in biopsy specimens of the antrum from normal subjects without hypergastrinemia, and from patients with hypergastrinemia not induced by gastrinoma or supra selective vagotomy. Compared with normal subjects, antral G cell density and G/D cell ratio were significantly increased in patients with hypergastrinemia. A significant correlation was found between G cell density or G/D cell ratio and the integrated gastrin output values. A quantitative estimation appears therefore possible in biopsy specimens.
对无高胃泌素血症的正常受试者以及非胃泌素瘤或超选择性迷走神经切断术所致高胃泌素血症患者的胃窦活检标本，估算每单位表面的胃泌素细胞（G细胞）和生长抑素细胞（D细胞）数量以及G/D细胞比率。与正常受试者相比，高胃泌素血症患者的胃窦G细胞密度和G/D细胞比率显著增加。发现G细胞密度或G/D细胞比率与胃泌素总输出值之间存在显著相关性。因此，对活检标本进行定量估计似乎是可行的。
