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泛发性发疹性角化棘皮瘤伴白癜风,继以痒疹结节形成:病例报告及文献复习。

Generalized eruptive keratoacanthoma with vitiligo followed by the development of prurigo nodularis: A case report and published work review.

机构信息

Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Department of Medical Cosmetology, Shanghai Dermatology Hospital, Shanghai, China.

出版信息

J Dermatol. 2018 Feb;45(2):211-215. doi: 10.1111/1346-8138.14106. Epub 2017 Oct 23.

Abstract

Herein, we report a unique case of generalized eruptive keratoacanthoma (GEKA) in a 47-year-old Chinese man presenting with extensive pruritic papules and nodules accompanied by oral lesions. He also had a 2-year history of vitiligo and long-term experience of working outdoors. Biopsies were consistent with keratoacanthoma . Interestingly, prurigo nodularis (PN) was found in histopathology at 1-year follow up. To our knowledge, this is the first report describing a case of GEKA with oral lesions complicated with vitiligo and developed with PN.

摘要

在此,我们报告了一例 47 岁中国男性的全身性发疹性角化棘皮瘤(GEKA),表现为广泛瘙痒性丘疹和结节,并伴有口腔病变。他还患有白癜风 2 年,长期在户外工作。活检符合角化棘皮瘤。有趣的是,在 1 年随访时的组织病理学中发现了结节性痒疹(PN)。据我们所知,这是首例描述口腔病变合并白癜风的 GEKA 病例,且并发了 PN。

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