Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Department of Medical Cosmetology, Shanghai Dermatology Hospital, Shanghai, China.
J Dermatol. 2018 Feb;45(2):211-215. doi: 10.1111/1346-8138.14106. Epub 2017 Oct 23.
Herein, we report a unique case of generalized eruptive keratoacanthoma (GEKA) in a 47-year-old Chinese man presenting with extensive pruritic papules and nodules accompanied by oral lesions. He also had a 2-year history of vitiligo and long-term experience of working outdoors. Biopsies were consistent with keratoacanthoma . Interestingly, prurigo nodularis (PN) was found in histopathology at 1-year follow up. To our knowledge, this is the first report describing a case of GEKA with oral lesions complicated with vitiligo and developed with PN.
在此，我们报告了一例 47 岁中国男性的全身性发疹性角化棘皮瘤（GEKA），表现为广泛瘙痒性丘疹和结节，并伴有口腔病变。他还患有白癜风 2 年，长期在户外工作。活检符合角化棘皮瘤。有趣的是，在 1 年随访时的组织病理学中发现了结节性痒疹（PN）。据我们所知，这是首例描述口腔病变合并白癜风的 GEKA 病例，且并发了 PN。
