Carr V, Wale J
Department of Psychiatry, University of Adelaide, South Australia.
J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1531-7. doi: 10.1136/jnnp.51.12.1531.
Perceptual asymmetry was measured in acutely psychotic schizophrenic patients and normal controls using a dichotic monitoring task. Although the schizophrenic group differed from the controls in terms of accuracy and speed of response, there were no significant group differences with respect to asymmetries in these variables. The pattern of responding in the schizophrenic group was also examined in relation to differences in symptomatology and antipsychotic drug administration. These variables, in isolation and in interaction with each other, were found to have a number of effects on both asymmetry and overall level of responding. The results were interpreted in the context of an information processing model of functional hemisphere asymmetry in schizophrenia, and the implications regarding the nature of schizophrenic symptomatology and the effects of antipsychotic drugs were discussed.
使用双耳分听监测任务，对急性精神病性精神分裂症患者和正常对照组的知觉不对称性进行了测量。尽管精神分裂症组在反应准确性和速度方面与对照组存在差异，但在这些变量的不对称性方面，两组之间没有显著差异。还研究了精神分裂症组的反应模式与症状差异和抗精神病药物给药之间的关系。发现这些变量单独以及相互作用时，对不对称性和总体反应水平都有多种影响。在精神分裂症功能性半球不对称性的信息处理模型背景下对结果进行了解释，并讨论了其对精神分裂症症状本质和抗精神病药物作用的影响。
