Ras Marten, Reitsma Johannes B, Hoes Arno W, Six Alfred Jacob, Poldervaart Judith M
Faculty of Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
BMJ Open. 2017 Oct 22;7(10):e017259. doi: 10.1136/bmjopen-2017-017259.
The HEART score can accurately stratify the risk of major adverse cardiac events (MACE) in patients with chest pain. We investigated the frequency, circumstances and potential consequences of errors in its calculation.
We performed a secondary analysis of a stepped wedge trial of patients with chest pain presenting to nine Dutch emergency departments. We recalculated HEART scores for all patients by re-evaluating the elements age (A), risk factors (R) and troponin (T) and compared these new scores with those given by physicians in daily practice. We investigated which circumstances increased the probability of incorrect scoring and explored the potential consequences.
The HEART score was incorrectly scored in 266 out of 1752 patients (15.2%; 95% CI 13.5% to 16.9%). Most errors occurred in the R ('Risk factors') element (61%). Time of admission, and patient's age or gender did not contribute to errors, but more errors were made in patients with higher scores. In 102 patients (5.8%, 95% CI 4.7% to 6.9%) the incorrect HEART score resulted in incorrect risk categorisation (too low or too high). Patients with an incorrectly calculated HEART score had a higher risk of MACE (OR 1.85; 95% CI 1.37 to 2.50), which was largely related to more errors being made in patients with higher HEART scores.
Our results show that the HEART score was incorrectly calculated in 15% of patients, leading to inappropriate risk categorisation in 5.8% which may have led to suboptimal clinical decision-making and management. Actions should be taken to improve the score's use in daily practice.
HEART评分能够准确地对胸痛患者发生主要不良心脏事件(MACE)的风险进行分层。我们研究了其计算错误的频率、情况及潜在后果。
我们对在荷兰9家急诊科就诊的胸痛患者进行的一项阶梯楔形试验进行了二次分析。通过重新评估年龄(A)、危险因素(R)和肌钙蛋白(T)等因素,我们重新计算了所有患者的HEART评分,并将这些新评分与医生在日常实践中给出的评分进行比较。我们研究了哪些情况会增加评分错误的可能性,并探讨了潜在后果。
1752例患者中有266例(15.2%;95%CI 13.5%至16.9%)的HEART评分计算错误。大多数错误发生在R(“危险因素”)因素中(61%)。入院时间、患者年龄或性别与错误无关,但评分较高的患者错误更多。在102例患者中(5.8%,95%CI 4.7%至6.9%),错误的HEART评分导致了错误的风险分类(过低或过高)。HEART评分计算错误的患者发生MACE的风险更高(OR 1.85;95%CI 1.37至2.50),这在很大程度上与HEART评分较高的患者错误更多有关。
我们的结果表明,15%的患者HEART评分计算错误,导致5.8%的患者风险分类不当,这可能导致临床决策和管理欠佳。应采取行动以改善该评分在日常实践中的应用。