Fisher Victoria L, Tahrani Abd A
School of Medicine, University of Nottingham, Nottingham.
Institute of Metabolism and Systems Research, University of Birmingham.
Diabetes Metab Syndr Obes. 2017 Oct 6;10:419-434. doi: 10.2147/DMSO.S129797. eCollection 2017.
Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular disease, chronic kidney disease, and morbidity in patients with DM, but despite these significant consequences CAN often remains undiagnosed for a prolonged period. This is commonly due to the disease being asymptomatic until the later stages, as well as a lack of easily available screening strategies. In this article, we review the latest developments in the epidemiology, pathogenesis, diagnosis, consequences, and treatments of CAN in patients with DM.
心脏自主神经病变（CAN）是糖尿病（DM）常见且常被漏诊的并发症。CAN与糖尿病患者死亡率增加、心血管疾病、慢性肾脏病及发病率相关，但尽管有这些严重后果，CAN往往在很长一段时间内仍未被诊断出来。这通常是由于该疾病在晚期之前没有症状，以及缺乏容易获得的筛查策略。在本文中，我们综述了糖尿病患者CAN在流行病学、发病机制、诊断、后果及治疗方面的最新进展。
