Ati Jihen, Lafite Pierre, Daniellou Richard
ICOA UMR CNRS 7311, University of Orléans, rue de Chartres, BP 6759, 45067 Orléans cedex 2, France.
Beilstein J Org Chem. 2017 Sep 5;13:1857-1865. doi: 10.3762/bjoc.13.180. eCollection 2017.
Carbohydrate related enzymes, like glycosyltransferases and glycoside hydrolases, are nowadays more easily accessible and are thought to represent powerful and greener alternatives to conventional chemical glycosylation procedures. The knowledge of their corresponding mechanisms has already allowed the development of efficient biocatalysed syntheses of complex -glycosides. These enzymes can also now be applied to the formation of rare or unnatural glycosidic linkages.
与碳水化合物相关的酶，如糖基转移酶和糖苷水解酶，如今更容易获得，并且被认为是传统化学糖基化方法的强大且更环保的替代方法。对其相应机制的了解已经使得能够开发出高效的生物催化合成复杂糖苷的方法。这些酶现在也可用于形成稀有或非天然的糖苷键。
