• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大卫·鲍伊与慢创新的艺术:生物技术和精准医疗全球发展的快反式赢家策略。

David Bowie and the Art of Slow Innovation: A Fast-Second Winner Strategy for Biotechnology and Precision Medicine Global Development.

机构信息

1 Independent Writer and Researcher, Innovation in Global Governance for Science, Technology and Health, Toronto, Ontario, Canada .

2 School of Biotechnology, Amrita Vishwa Vidyapeetham (Amrita University) , Kollam, India .

出版信息

OMICS. 2017 Nov;21(11):633-637. doi: 10.1089/omi.2017.0148. Epub 2017 Oct 24.

DOI:10.1089/omi.2017.0148
PMID:29064337
Abstract

Original ideas and innovation cannot always be ordered like a courier service and delivered fresh to our desk at 9 am. Yet, most creativity-based organizations, careers, and professions, science and biotechnology innovation included, emphasize the speed as the prevailing ideology. But a narrow focus on speed has several and overlooked shortcomings. For example, it does not offer the opportunity to draw from, and stitch together disparate concepts and practices for truly disruptive innovation. Preventing false starts, learning from others' or our own mistakes, and customizing innovations for local community needs are difficult in a speed-hungry innovation ecosystem. We introduce a new strategy, the Fast-Second Winner, specifically in relation to global development of biotechnologies and precision medicine. This à la carte global development strategy envisions a midstream entry into the innovation ecosystem. Moreover, we draw from the works of the late David Bowie who defied rigid classifications as an artist and prolific innovator, and introduce the concept and practice of slow innovation that bodes well with the Fast-Second Winner strategy. A type of slow innovation, the Fast-Second Winner is actually fast and sustainable in the long term, and efficient by reducing false starts in new precision medicine application contexts and geographies, learning from other innovators' failures, and shaping innovations for the local community needs. The establishment of Centers for Fast-Second Innovation (CFSIs), and their funding, for example, by crowdfunding and other innovative mechanisms, could be timely for omics and precision medicine global development. If precision medicine is about tailoring drug treatments and various health interventions to individuals, we suggest to start from tailoring new ideas, and focus not only on how much we innovate but also what and how we innovate. In principle, the Fast-Second Winner can be applied to omics and other biotechnology responsible development in medical practice or any field of applied innovation.

摘要

原创想法和创新不能总是像快递服务一样,在早上 9 点准时送到我们的办公桌上。然而,大多数以创造力为基础的组织、职业和专业,包括科学和生物技术创新,都强调速度是主导思想。但是,对速度的狭隘关注有几个被忽视的缺点。例如,它没有提供机会,从不同的概念和实践中汲取灵感,并将其整合在一起,以实现真正的颠覆性创新。在一个热衷于速度的创新生态系统中,防止错误的开始、从他人或自己的错误中学习以及为当地社区的需求定制创新都是很困难的。我们引入了一种新策略,即“快速第二赢家”,特别是在全球生物技术和精准医学的发展方面。这种定制化的全球发展策略设想在创新生态系统中进行中游进入。此外,我们借鉴了已故大卫·鲍伊的作品,他拒绝了作为一名艺术家和多产创新者的僵化分类,并引入了慢创新的概念和实践,这与“快速第二赢家”策略相得益彰。作为一种慢创新,“快速第二赢家”实际上在长期内是快速和可持续的,并且通过减少新的精准医学应用背景和地理环境中的错误开始、从其他创新者的失败中学习以及为当地社区的需求塑造创新,具有效率。例如,通过众筹和其他创新机制,为快速第二创新中心(CFSIs)的建立及其提供资金,可能会及时促进组学和精准医学的全球发展。如果精准医学是关于为个人量身定制药物治疗和各种健康干预措施,那么我们建议从量身定制新想法开始,不仅关注我们创新的多少,还要关注我们创新的内容和方式。原则上,“快速第二赢家”可以应用于医学实践或任何应用创新领域的组学和其他生物技术的负责任发展。

相似文献

1
David Bowie and the Art of Slow Innovation: A Fast-Second Winner Strategy for Biotechnology and Precision Medicine Global Development.大卫·鲍伊与慢创新的艺术:生物技术和精准医疗全球发展的快反式赢家策略。
OMICS. 2017 Nov;21(11):633-637. doi: 10.1089/omi.2017.0148. Epub 2017 Oct 24.
2
Genomic Medicine Without Borders: Which Strategies Should Developing Countries Employ to Invest in Precision Medicine? A New "Fast-Second Winner" Strategy.无国界基因组医学:发展中国家应采用哪些策略投资精准医学?一种新的“快速第二赢家”策略。
OMICS. 2017 Nov;21(11):647-657. doi: 10.1089/omi.2017.0141.
3
Precision Nutrition 4.0: A Big Data and Ethics Foresight Analysis--Convergence of Agrigenomics, Nutrigenomics, Nutriproteomics, and Nutrimetabolomics.精准营养4.0:大数据与伦理前瞻性分析——农业基因组学、营养基因组学、营养蛋白质组学和营养代谢组学的融合
OMICS. 2016 Feb;20(2):69-75. doi: 10.1089/omi.2015.0193. Epub 2016 Jan 19.
4
Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics).伯纳德·勒勒:2014年首届全球组学与个性化医学沃纳·卡洛负责任创新奖获得者(环太平洋临床药物遗传学协会)
OMICS. 2014 Apr;18(4):211-21. doi: 10.1089/omi.2014.0029. Epub 2014 Mar 20.
5
Rebooting Bioresilience: A Multi-OMICS Approach to Tackle Global Catastrophic Biological Risks and Next-Generation Biothreats.重启生物弹性:一种应对全球灾难性生物风险和新一代生物威胁的多组学方法。
OMICS. 2018 Jan;22(1):35-51. doi: 10.1089/omi.2017.0185.
6
Digging Deeper into Precision/Personalized Medicine: Cracking the Sugar Code, the Third Alphabet of Life, and Sociomateriality of the Cell.深入探讨精准/个性化医学:破解生命的第三个字母——糖码,以及细胞的社会物质性。
OMICS. 2020 Feb;24(2):62-80. doi: 10.1089/omi.2019.0220. Epub 2020 Jan 28.
7
Translational -omics: Future potential and current challenges in precision medicine.转化组学:精准医学的未来潜力和当前挑战。
Methods. 2018 Dec 1;151:3-11. doi: 10.1016/j.ymeth.2018.05.009. Epub 2018 May 22.
8
Beware the Medical-Industrial Complex.警惕医疗产业联合体。
Oncologist. 1996;1(4):IV-V.
9
Big data-driven precision medicine: Starting the custom-made era of iatrology.大数据驱动的精准医学:开启定制化的医学时代。
Biomed Pharmacother. 2020 Sep;129:110445. doi: 10.1016/j.biopha.2020.110445. Epub 2020 Jun 24.
10
How Do You Start a Revolution for Systems Medicine in a Health Innovation Ecosystem? Think Orthogonally and Change Assumptions.如何在健康创新生态系统中掀起系统医学革命?从正交思维出发,改变固有观念。
OMICS. 2024 Oct;28(10):489-491. doi: 10.1089/omi.2024.0173. Epub 2024 Sep 18.

引用本文的文献

1
3D genomics and its applications in precision medicine.三维基因组学及其在精准医学中的应用。
Cell Mol Biol Lett. 2023 Mar 6;28(1):19. doi: 10.1186/s11658-023-00428-x.
2
Roadmap for Establishing Large-Scale Genomic Medicine Initiatives in Low- and Middle-Income Countries.建立中低收入国家大规模基因组医学计划的路线图。
Am J Hum Genet. 2020 Oct 1;107(4):589-595. doi: 10.1016/j.ajhg.2020.08.005.
3
Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery.21 世纪的药物发现中的天然产物:新药发现的创新。
Int J Mol Sci. 2018 May 25;19(6):1578. doi: 10.3390/ijms19061578.