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慢性肾脏病对勃起功能的阶段效应。

Stage effect of chronic kidney disease in erectile function.

机构信息

Escola Médica da Universidade Federal de Goiás, GO Brasil.

Mercy Holy House, Goiânia, GO, Brasil.

出版信息

Int Braz J Urol. 2018 Jan-Feb;44(1):132-140. doi: 10.1590/S1677-5538.IBJU.2017.0228.

DOI:10.1590/S1677-5538.IBJU.2017.0228
PMID:29064656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5815543/
Abstract

PURPOSE

The study aims to assess the influence of the stage of chronic kidney disease and glomerular filtration rate on prevalence and degree of erectile dysfunction.

MATERIALS AND METHODS

This transversal study, conducted from May 2013 to December 2015, included patients with chronic kidney disease in conservative treatment, stages III/IV/V. Erectile dysfunction was evaluated by the International Index of Erectile Function. Data classically associated with erectile dysfunction were obtained by medical record review. Erectile dysfunction, degree of erectile dysfunction, and other main variables associated with erectile dysfunction were compared between patients with chronic kidney disease on conservative treatment stages III versus IV/V using the Chi-square test. The relationship between score of the International Index of Erectile Dysfunction and glomerular filtration rate was established by Pearson correlation coefficient.

RESULTS

Two hundred and forty five patients with chronic kidney disease in con-servative treatment participated of the study. The prevalence of erectile dysfunction in patients with chronic kidney disease in stages IV/V was greater than in stage III. Glomerular filtration rate positively correlated with score of the International Index of Erectile Dysfunction.

CONCLUSIONS

The study suggests that chronic kidney disease progression (glomerular filtration rate decrease and advance in chronic kidney disease stages) worsen erectile function. Hypothetically, diagnosis and treatment of erectile dysfunction may be anticipated with the analysis of chronic kidney disease progression.

摘要

目的

本研究旨在评估慢性肾脏病分期和肾小球滤过率对勃起功能障碍患病率和严重程度的影响。

材料与方法

本横断面研究于 2013 年 5 月至 2015 年 12 月进行，纳入接受保守治疗的慢性肾脏病 III/IV/V 期患者。采用国际勃起功能指数评估勃起功能障碍。通过病历回顾获得与勃起功能障碍相关的经典数据。采用卡方检验比较接受保守治疗的慢性肾脏病 III 期与 IV/V 期患者之间的勃起功能障碍、勃起功能障碍严重程度和其他与勃起功能障碍相关的主要变量。通过皮尔逊相关系数建立国际勃起功能指数评分与肾小球滤过率之间的关系。

结果

245 例接受保守治疗的慢性肾脏病患者参与了本研究。IV/V 期慢性肾脏病患者勃起功能障碍的患病率大于 III 期。肾小球滤过率与国际勃起功能指数评分呈正相关。

结论

本研究提示慢性肾脏病进展（肾小球滤过率下降和慢性肾脏病分期进展）会使勃起功能恶化。推测通过分析慢性肾脏病的进展，可以更早地诊断和治疗勃起功能障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/59a3f811f420/1677-5538-ibju-44-01-0132-gf06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/000e2b9de720/1677-5538-ibju-44-01-0132-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/42cae4108fa3/1677-5538-ibju-44-01-0132-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/788a85c67611/1677-5538-ibju-44-01-0132-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/5eb684a60705/1677-5538-ibju-44-01-0132-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/8ff9a309d2a6/1677-5538-ibju-44-01-0132-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/59a3f811f420/1677-5538-ibju-44-01-0132-gf06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/000e2b9de720/1677-5538-ibju-44-01-0132-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/42cae4108fa3/1677-5538-ibju-44-01-0132-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/788a85c67611/1677-5538-ibju-44-01-0132-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/5eb684a60705/1677-5538-ibju-44-01-0132-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/8ff9a309d2a6/1677-5538-ibju-44-01-0132-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ce/5815543/59a3f811f420/1677-5538-ibju-44-01-0132-gf06.jpg

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