Department of Occupational Medicine (Dr Tsao, Dr Luo); Department of Dermatology (Dr Chang); Department of Laboratory Medicine (Dr Gu), Chang Gung Memorial Hospital, Linkou; Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City (Dr Tzeng); Department of Statistics, National Taipei University, Taipei (Dr Tzeng); and College of Medicine, Chang Gung University (Dr Tsao, Dr Luo), Taoyuan, Taiwan, R.O.C.
J Occup Environ Med. 2018 Apr;60(4):337-342. doi: 10.1097/JOM.0000000000001204.
To investigate health problems, especially pulmonary function, among electroplating workers exposed to nickel.
We recruited 153 nickel-exposed and 74 control workers from electroplating shops in printed circuit board production plants. Questionnaires were conducted to collect basic information. Symptoms and pulmonary function were ascertained.
The average urine nickel level of the 79 high-exposure, 74 low-exposure, and 74 control workers were 7.38 ± 5.96, 5.79 ± 4.75, and 5.27 ± 3.89 μg/g Cr, respectively. Nickel-exposed workers had a significantly higher incidence of skin- and airway-based symptoms. A significant relationship between impaired pulmonary function and high (more than5.2 μg/g Cr) urine nickel level was observed.
Nickel-exposed workers had significantly higher urine nickel levels with more skin-, airway-based symptoms, as well as impaired pulmonary function. A dose-response relationship between decreased pulmonary function and nickel exposure status was observed.
调查镍暴露电镀工人的健康问题，特别是肺部功能。
我们从电路板生产厂的电镀车间招募了 153 名镍暴露工人和 74 名对照工人。通过问卷调查收集基本信息。确定症状和肺功能。
79 名高暴露、74 名低暴露和 74 名对照工人的平均尿镍水平分别为 7.38±5.96、5.79±4.75 和 5.27±3.89μg/g Cr。镍暴露工人的皮肤和气道症状发生率明显较高。观察到肺功能受损与高（超过 5.2μg/g Cr）尿镍水平之间存在显著关系。
镍暴露工人的尿镍水平明显较高，皮肤和气道症状以及肺功能受损更为明显。观察到肺功能下降与镍暴露状态之间存在剂量反应关系。
