Kazan National Research Technical University named after A. N. Tupolev (KAI), Kazan, Russia.
The I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
J Healthc Eng. 2017;2017:3471616. doi: 10.1155/2017/3471616. Epub 2017 Jul 16.
Models that describe the trace element status formation in the human organism are essential for a correction of micromineral (trace elements) deficiency. A direct trace element retention assessment in the body is difficult due to the many internal mechanisms. The trace element retention is determined by the amount and the ratio of incoming and excreted substance. So, the concentration of trace elements in drinking water characterizes the intake, whereas the element concentration in urine characterizes the excretion. This system can be interpreted as three interrelated elements that are in equilibrium. Since many relationships in the system are not known, the use of standard mathematical models is difficult. The artificial neural network use is suitable for constructing a model in the best way because it can take into account all dependencies in the system implicitly and process inaccurate and incomplete data. We created several neural network models to describe the retentions of trace elements in the human body. On the model basis, we can calculate the microelement levels in the body, knowing the trace element levels in drinking water and urine. These results can be used in health care to provide the population with safe drinking water.
描述人体微量元素状态形成的模型对于纠正微量矿物质(微量元素)缺乏症至关重要。由于存在许多内部机制,因此直接评估体内微量元素保留情况较为困难。微量元素的保留取决于摄入和排泄物质的数量和比例。因此,饮用水中微量元素的浓度可表征摄入量,而尿液中的元素浓度则可表征排泄量。该系统可以解释为三个相互关联的处于平衡状态的元素。由于系统中的许多关系都不为人知,因此很难使用标准的数学模型。人工神经网络的使用非常适合以最佳方式构建模型,因为它可以隐式考虑系统中的所有依赖性,并处理不准确和不完整的数据。我们创建了几个神经网络模型来描述人体对微量元素的保留情况。在此模型基础上,我们可以计算出体内的微量元素水平,已知饮用水和尿液中的微量元素水平。这些结果可用于保健领域,为人们提供安全的饮用水。