Furuse Junji
Dept. of Medical Oncology, Kyorin University Faculty of Medicine.
Gan To Kagaku Ryoho. 2017 Oct;44(10):827-830.
Pancreatic cancer, adenocarcinoma, generally rapidly progresses, and if a metastatic lesion is detected, chemotherapy is applied even in solitary metastasis. However, surgical resection for solitary metastasis have been reported to achieve long survival in some pancreatic cancer patients. In a prospective study of surgery for hepatic and lymph node oligometastasis of pancreatic cancer, long survival of 5 years or more was reported around 10%. Furthermore, longer survival and fewer rerecurrence were achieved with surgery in lung metastasis than in liver metastasis and loco-regional recurrence. Although there has been no establishment of concept or no consensus of treatment strategy for oligometastasis in pancreatic cancer, some patients with pancreatic cancer have long disease-free survival by surgery for oligometastasis. A population of pancreatic cancer patients who have benefits of surgery for oligometastasis should be identified, and it is necessary to establish treatments for oligometastasis as standard treatments in pancreatic cancer.
胰腺癌，腺癌，通常进展迅速，如果检测到转移病灶，即使是孤立转移也会进行化疗。然而，据报道，对于一些胰腺癌患者，孤立转移灶的手术切除可实现长期生存。在一项关于胰腺癌肝和淋巴结寡转移手术的前瞻性研究中，报告称5年或更长时间的长期生存率约为10%。此外，与肝转移和局部区域复发相比，肺转移手术可实现更长的生存期和更少的再复发。虽然胰腺癌寡转移的概念尚未确立，治疗策略也未达成共识，但一些胰腺癌患者通过寡转移手术可实现长期无病生存。应该确定能从寡转移手术中获益的胰腺癌患者群体，并且有必要将寡转移治疗确立为胰腺癌的标准治疗方法。
