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巴巴多斯胰岛素问题(BIM)研究:加勒比海岛国巴巴多斯基于人群的2型糖尿病患者样本中胰岛素治疗的障碍

The Barbados Insulin Matters (BIM) study: Barriers to insulin therapy among a population-based sample of people with type 2 diabetes in the Caribbean island of Barbados.

作者信息

Taylor Charles G, Taylor Gordon, Atherley Anique, Hambleton Ian, Unwin Nigel, Adams O Peter

机构信息

Faculty of Medical Sciences, University of the West Indies, Cave Hill Campus, St. Michael, Barbados.

1 West 5.115, Department for Health, University of Bath, Claverton Down, BA2 7AY, United Kingdom.

出版信息

J Clin Transl Endocrinol. 2017 May 4;8:49-53. doi: 10.1016/j.jcte.2017.04.002. eCollection 2017 Jun.

Abstract

AIM

The purpose of this study was to document in people with type 2 diabetes (T2DM) in Barbados, attitudes and beliefs that may result in psychological insulin resistance.

METHODS

A representative, population-based, sample of 175 eligible people with T2DM 25 years of age and over was surveyed by telephone. The 20-item insulin treatment appraisal scale (ITAS) was administered (score range 20 to 100 for positive to negative perceptions).

RESULTS

117 people participated (67% response rate, 32% male, mean age 66 years, 90% Black, 22% on insulin). Of non-responders, 52 were not contactable and 6 were difficult to communicate with. Negative perceptions about insulin use included - meant a worsening of diabetes (68%), would worry family (63%), feared self-injection (58%), meant a failure in self-management (57%), injections were painful (54%), would be seen as being sicker (46%), increased hypoglycaemia risk (38%), required effort (34%), causes weight gain (27%), causes a deterioration in health (14%), and would have to give up enjoyable activities (10%). Positive perceptions were - helps good glycaemic control (78%), would prevent complications (61%) and improves health (58%). Mean total ITAS score (61.6, SD = 7.7) was lower for those on insulin compared to those not on insulin (53.7 vs. 63.8,  < 0.0001). Sex, age and diabetes diagnosis duration were not significant predictors of ITAS score.

CONCLUSIONS

Multiple factors related to patient beliefs and attitudes need to be considered and addressed when initiating insulin in order to minimise psychological insulin resistance and delay. Patients using insulin had less negative perceptions than those not on insulin.

摘要

目的

本研究旨在记录巴巴多斯2型糖尿病(T2DM)患者中可能导致心理性胰岛素抵抗的态度和信念。

方法

通过电话对175名年龄在25岁及以上的符合条件的T2DM患者进行了一项具有代表性的、基于人群的抽样调查。采用了20项胰岛素治疗评估量表(ITAS)(得分范围为20至100,代表从积极到消极的认知)。

结果

117人参与了调查(应答率为67%,男性占32%,平均年龄66岁,90%为黑人,22%使用胰岛素)。在未应答者中,52人无法联系上,6人难以沟通。对胰岛素使用的负面认知包括——意味着糖尿病病情恶化(68%)、会让家人担心(63%)、害怕自我注射(58%)、意味着自我管理失败(57%)、注射疼痛(54%)、会被视为病情更严重(46%)、低血糖风险增加(38%)、需要付出努力(34%)、导致体重增加(27%)、导致健康状况恶化(14%)以及不得不放弃喜欢的活动(10%)。正面认知包括——有助于良好的血糖控制(78%)、可预防并发症(61%)以及改善健康(58%)。与未使用胰岛素的患者相比,使用胰岛素的患者的ITAS总分均值(61.6,标准差=7.7)更低(53.7对63.8,<0.0001)。性别、年龄和糖尿病诊断时长不是ITAS得分的显著预测因素。

结论

在开始使用胰岛素时,需要考虑并解决与患者信念和态度相关的多个因素,以尽量减少心理性胰岛素抵抗和延迟。使用胰岛素的患者的负面认知比未使用胰岛素的患者少。

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本文引用的文献

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Barbados Insulin Matters (BIM) study: Perceptions on insulin initiation by primary care doctors in the Caribbean island of Barbados.
Prim Care Diabetes. 2017 Apr;11(2):140-147. doi: 10.1016/j.pcd.2016.10.001. Epub 2016 Nov 4.
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Diabet Med. 2010 Feb;27(2):169-74. doi: 10.1111/j.1464-5491.2009.02904.x.
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