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[生长抑素不改变大鼠肠上皮细胞对3-氧甲基葡萄糖和亮氨酸的摄取]

[Somatostatin does not modify 3-oxymethylglucose and leucine uptake by rat enterocytes].

作者信息

Crespo C A, Martínez-Sapiña J, Taboada M C

机构信息

Departamento de Fisiología Facultad de Farmacia, Santiago de Compostela, España.

出版信息

Rev Esp Fisiol. 1988 Sep;44(3):283-6.

PMID:2906751
Abstract

The effects of somatostatin on 3-oxymethylglucose (3-OMG) and leucine uptake by rat enterocytes were examined. Somatostatin did not decrease the 3-OMG enterocyte uptake. When the 3-OMG active transport was inhibited by phloridzin, Somatostatin presented no significant modifications. Somatostatin showed a slight decrease in 3-OMG release through the basolateral membrane, when such a release was inhibited with theophylline. Somatostatin did not modify the intestinal leucine uptake or its inhibition by methionine.

摘要

研究了生长抑素对大鼠肠上皮细胞摄取3-氧甲基葡萄糖(3-OMG)和亮氨酸的影响。生长抑素并未降低肠上皮细胞对3-OMG的摄取。当根皮苷抑制3-OMG的主动转运时,生长抑素无显著变化。当用茶碱抑制3-OMG通过基底外侧膜的释放时,生长抑素使其释放略有减少。生长抑素未改变肠道对亮氨酸的摄取或蛋氨酸对其的抑制作用。

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