Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, B3H 4R2, Canada.
X-ray Crystallography Laboratory, Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
Angew Chem Int Ed Engl. 2017 Dec 11;56(50):15901-15904. doi: 10.1002/anie.201709441. Epub 2017 Nov 15.
A new (N-phosphinoamidinate)manganese complex is shown to be a useful pre-catalyst for the hydrosilative reduction of carbonyl compounds, and in most cases at room temperature. The Mn-catalyzed reduction of tertiary amides to tertiary amines, with a useful scope, is demonstrated for the first time by use of this catalyst, and is competitive with the most effective transition-metal catalysts known for such transformations. Ketones, aldehydes, and esters were also successfully reduced under mild conditions by using this new Mn catalyst.
一种新型（N-膦酰胺基）锰配合物被证明是一种有用的前催化剂，可用于羰基化合物的硅氢还原，大多数情况下在室温下即可进行。首次使用该催化剂证明了 Mn 催化的叔酰胺还原为叔胺具有广泛的应用范围，并且与用于此类转化的最有效过渡金属催化剂具有竞争力。在温和条件下，使用这种新型 Mn 催化剂还成功地还原了酮、醛和酯。
