Légaré Lavergne Julien, To Hoang-Minh, Fontaine Frédéric-Georges
Département de Chimie, Université Laval 1045 Avenue de la Médecine Québec G1V 0A6 Québec Canada
RSC Adv. 2021 Sep 28;11(51):31941-31949. doi: 10.1039/d1ra05945a. eCollection 2021 Sep 27.
We report that boric acid, BOH, is a good precatalyst for the BH-catalyzed hydroboration of esters using pinacolborane as a borylation agent. Using microwave irradiation as an energy source, we demonstrated that a dozen esters were converted into the corresponding boronate ethers in good yields. It was also possible to use boric acid as a precatalyst to reduce carbonates and alkynes. Considering the hazardous and pyrophoric nature of BH solutions, boric acid proves to be a safe and green precatalyst for the metal-free reduction of unsaturated species.
我们报道,硼酸(BOH)是使用频哪醇硼烷作为硼化剂时,用于BH催化酯的硼氢化反应的良好前催化剂。以微波辐射作为能源,我们证明了十几种酯能以良好的产率转化为相应的硼酸酯醚。使用硼酸作为前催化剂来还原碳酸酯和炔烃也是可行的。考虑到BH溶液具有危险性和自燃性,硼酸被证明是用于不饱和物种无金属还原的安全且绿色的前催化剂。