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钌(0)催化的 1,2-二醇、酮醇或二酮通过醇介导的氢转移的环加成反应。

Ruthenium(0)-Catalyzed Cycloaddition of 1,2-Diols, Ketols, or Diones via Alcohol-Mediated Hydrogen Transfer.

机构信息

University of Texas at Austin, Department of Chemistry, Welch Hall (A5300), 105 E 24th St., Austin, TX, 78712, USA.

出版信息

Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3012-3021. doi: 10.1002/anie.201709916. Epub 2018 Feb 6.

DOI:10.1002/anie.201709916
PMID:29068505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5842109/
Abstract

Merging the characteristics of transfer hydrogenation and carbonyl addition, a broad new class of ruthenium(0)-catalyzed cycloadditions has been developed. As discussed in this Minireview, fused or bridged bicyclic ring systems are accessible in a redox-independent manner in C-C bond-forming hydrogen transfer reactions of diols, α-ketols, or 1,2-diones with diverse unsaturated reactants.

摘要

结合转移氢化和羰基加成的特点，开发了一类新的钌（0）催化环加成反应。正如本篇综述中讨论的，二醇、α-酮醇或 1,2-二酮与各种不饱和反应物在 C-C 键形成的氢转移反应中，可以以不依赖氧化还原的方式得到稠合或桥连双环体系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f9a/5842109/d185656d9777/nihms929608f15.jpg
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