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开发并体外验证了一种简化的数值模型,用于设计仿生股骨柄。

Development and in vitro validation of a simplified numerical model for the design of a biomimetic femoral stem.

机构信息

Ecole de technologie superieure, Department of Mechanical Engineering, 1100 Notre-Dame Street West, Montreal, Quebec, Canada H3C1K3.

出版信息

J Mech Behav Biomed Mater. 2018 Jan;77:539-550. doi: 10.1016/j.jmbbm.2017.10.019. Epub 2017 Oct 16.

DOI:10.1016/j.jmbbm.2017.10.019
PMID:29069636
Abstract

BACKGROUND

Dense and stiff metallic femoral stems implanted into femurs for total hip arthroplasties produce a stress shielding effect since they modify the original load sharing path in the bony structure. Consequently, in the long term, the strain adaptive nature of bones leads to bone resorption, implant loosening, and the need for arthroplasty revision. The design of new cementless femoral stems integrating open porous structures can reduce the global stiffness of the stems, allowing them a better match with that of bones and provide their firm fixation via bone ingrowth, and, thus reduce the risk of implantation failure.

METHODS

This paper aims to develop and validate a simplified numerical model of stress shielding, which calculates the levels of bone resorption or formation by comparing strain distributions on the surface of the intact and the implanted femurs subjected to a simulated biological loading. Two femoral stems produced by laser powder-bed fusion using Ti-6Al-4V alloy are employed: the first is fully dense, while the second features a diamond cubic lattice structure in its core. The validation consists of a comparison of the numerically calculated force-displacement diagrams, and displacement and strain fields with their experimental equivalents obtained using the digital image correlation technique.

RESULTS AND CONCLUSIONS

The numerical models showed reasonable agreement between the force-displacement diagrams. Also, satisfactory results for the correlation analyses of the total displacement and equivalent strain fields were obtained. The stress shielding effect of the implant was assessed by comparing the equivalent strain fields of the implanted and intact femurs. The results obtained predicted less bone resorption in the femur implanted with the porous stem than with its dense counterpart.

摘要

背景

全髋关节置换术中,将致密且僵硬的金属股骨柄植入股骨中会产生应力屏蔽效应,因为它们改变了骨结构中原有的载荷分担路径。因此,从长远来看,骨骼的应变适应性会导致骨吸收、植入物松动以及需要进行关节翻修。设计新的整合开放式多孔结构的非骨水泥股骨柄可以降低柄的整体刚度,使其更好地与骨骼匹配,并通过骨长入提供牢固的固定,从而降低植入失败的风险。

方法

本文旨在开发和验证一种简化的应力屏蔽数值模型,该模型通过比较完整和植入股骨在模拟生物载荷下表面的应变分布来计算骨吸收或形成的水平。采用激光粉末床熔覆技术用 Ti-6Al-4V 合金制造了两种股骨柄:一种是完全致密的,另一种是核心为立方晶格结构的。验证包括比较数值计算的力-位移图以及使用数字图像相关技术获得的实验等效位移和应变场。

结果与结论

数值模型在力-位移图上表现出较好的一致性。此外,总位移和等效应变场的相关分析也取得了令人满意的结果。通过比较植入和完整股骨的等效应变场来评估植入物的应力屏蔽效应。结果表明,多孔柄植入的股骨中骨吸收较少。

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