Shende Ravindra, Patel Ganesh
Department of Radiation Oncology, Capitol Hospital, Jalandhar, India.
Department of Radiation Oncology, AIIMS, Rishikesh, India.
Rep Pract Oncol Radiother. 2017 Nov-Dec;22(6):485-494. doi: 10.1016/j.rpor.2017.09.001. Epub 2017 Oct 21.
Objective of present study is to determine optimum value of DLG and its validation prior to being incorporated in TPS for Varian TrueBeam™ millennium 120 leaves MLC.
Partial transmission through the rounded leaf ends of the Multi Leaf Collimator (MLC) causes a conflict between the edges of the light field and radiation field. Parameter account for this partial transmission is called Dosimetric Leaf Gap (DLG). The complex high precession technique, such as Intensity Modulated Radiation Therapy (IMRT), entails the modeling of optimum value of DLG inside Eclipse Treatment Planning System (TPS) for precise dose calculation.
Distinct synchronized uniformed extension of sweeping dynamic MLC leaf gap fields created by Varian MLC shaper software were use to determine DLG. DLG measurements performed with both 0.13 cc semi-flex ionization chamber and 2D-Array I-Matrix were used to validate the DLG; similarly, values of DLG from TPS were estimated from predicted dose. Similar mathematical approaches were employed to determine DLG from delivered and TPS predicted dose. DLG determined from delivered dose measured with both ionization chamber (DLG) and I-Matrix (DLG) compared with DLG estimate from TPS predicted dose (DLG). Measurements were carried out for all available 6MV, 10MV, 15MV, 6MVFFF and 10MVFFF beam energies.
Maximum and minimum DLG deviation between measured and TPS calculated DLG was found to be 0.2 mm and 0.1 mm, respectively. Both of the measured DLGs (DLG and DLG) were found to be in a very good agreement with estimated DLG from TPS (DLG).
Proposed method proved to be helpful in verifying and validating the DLG value prior to its clinical implementation in TPS.
本研究的目的是确定剂量学叶片间距(DLG)的最佳值,并在将其纳入瓦里安TrueBeam™ 120叶 Millennium多叶准直器(MLC)的治疗计划系统(TPS)之前进行验证。
通过多叶准直器(MLC)圆形叶端的部分透射导致光野和辐射野边缘之间存在冲突。用于解释这种部分透射的参数称为剂量学叶片间距(DLG)。复杂的高精度技术,如调强放射治疗(IMRT),需要在Eclipse治疗计划系统(TPS)中对DLG的最佳值进行建模,以进行精确的剂量计算。
使用瓦里安MLC成型软件创建的不同同步均匀扩展的扫描动态MLC叶片间距场来确定DLG。使用0.13 cc半柔性电离室和二维阵列I-Matrix进行的DLG测量用于验证DLG;同样,从TPS预测剂量估计DLG值。采用类似的数学方法从交付剂量和TPS预测剂量中确定DLG。将用电离室(DLG)和I-Matrix(DLG)测量的交付剂量确定的DLG与TPS预测剂量(DLG)估计的DLG进行比较。对所有可用的6MV、10MV、15MV、6MVFFF和10MVFFF束能量进行测量。
测量的DLG与TPS计算的DLG之间的最大和最小偏差分别为0.2毫米和0.1毫米。发现两个测量的DLG(DLG和DLG)与TPS估计的DLG(DLG)非常吻合。
所提出的方法被证明有助于在TPS临床实施之前验证和确认DLG值。