Neethirajan Suresh, Ahmed Syed Rahin, Chand Rohit, Buozis John, Nagy Éva
BioNano Laboratory, School of Engineering, University of Guelph, Guelph, ON N1G 2W1, Canada.
Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.
Nanotheranostics. 2017 Jul 5;1(3):272-295. doi: 10.7150/ntno.20301. eCollection 2017.
Outbreaks of foodborne diseases related to fresh produce have been increasing in North America and Europe. Viral foodborne pathogens are poorly understood, suffering from insufficient awareness and surveillance due to the limits on knowledge, availability, and costs of related technologies and devices. Current foodborne viruses are emphasized and newly emerging foodborne viruses are beginning to attract interest. To face current challenges regarding foodborne pathogens, a point-of-care (POC) concept has been introduced to food testing technology and device. POC device development involves technologies such as microfluidics, nanomaterials, biosensors and other advanced techniques. These advanced technologies, together with the challenges in developing foodborne virus detection assays and devices, are described and analysed in this critical review. Advanced technologies provide a path forward for foodborne virus detection, but more research and development will be needed to provide the level of manufacturing capacity required.
在北美和欧洲，与新鲜农产品相关的食源性疾病暴发事件一直在增加。人们对食源性病毒病原体了解甚少，由于相关技术和设备在知识、可用性和成本方面的限制，导致认识不足且监测不力。当前的食源性病毒受到关注，新出现的食源性病毒也开始引起人们的兴趣。为应对当前食源性病原体带来的挑战，即时检测（POC）概念已被引入食品检测技术和设备中。POC设备的开发涉及微流体、纳米材料、生物传感器等技术以及其他先进技术。在这篇批判性综述中，将对这些先进技术以及开发食源性病毒检测方法和设备所面临的挑战进行描述和分析。先进技术为食源性病毒检测提供了一条前进的道路，但还需要更多研发工作来达到所需的制造能力水平。
