Zhu Xiaoning, Kim Tai-Yong, Kim Se-Min, Luo Ke, Lim Min-Cheol
College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong Province 266003, People's Republic of China.
Research Group of Food Safety and Distribution, Korea Food Research Institute (KFRI), Wanju-gun, Jeollabuk-do 55365, Republic of Korea.
J Agric Food Chem. 2023 Nov 1;71(43):15942-15953. doi: 10.1021/acs.jafc.3c05166. Epub 2023 Oct 20.
Viral foodborne diseases cause serious harm to human health and the economy. Rapid, accurate, and convenient approaches for detecting foodborne viruses are crucial for preventing diseases. Biosensors integrating electrochemical and optical properties of nanomaterials have emerged as effective tools for the detection of viruses in foods. However, they still face several challenges, including substantial sample preparation and relatively poor sensitivity due to complex food matrices, which limit their field applications. Hence, the purpose of this review is to provide an overview of recent advances in biosensing techniques, including electrochemical, SERS-based, and colorimetric biosensors, for detecting viral particles in food samples, with emerging techniques for extraction/concentration of virus particles from food samples. Moreover, the principle, design, and advantages/disadvantages of each biosensing method are comprehensively described. This review covers the recent development of rapid and sensitive biosensors that can be used as new standards for monitoring food safety and food quality in the food industry.
食源性病毒疾病对人类健康和经济造成严重危害。快速、准确且便捷的食源性病毒检测方法对于预防疾病至关重要。整合纳米材料电化学和光学特性的生物传感器已成为检测食品中病毒的有效工具。然而，它们仍面临若干挑战，包括大量的样品制备以及由于复杂食品基质导致的相对较差的灵敏度，这限制了它们的现场应用。因此，本综述的目的是概述生物传感技术的最新进展，包括电化学、基于表面增强拉曼光谱（SERS）和比色生物传感器，用于检测食品样品中的病毒颗粒，以及从食品样品中提取/浓缩病毒颗粒的新兴技术。此外，还全面描述了每种生物传感方法的原理、设计及优缺点。本综述涵盖了快速灵敏生物传感器的最新进展，这些生物传感器可作为食品工业中监测食品安全和食品质量的新标准。
