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卢旺达农村地区未治疗外科疾病的患病率:布勒拉区基于人群的横断面研究

Prevalence of Untreated Surgical Conditions in Rural Rwanda: A Population-Based Cross-sectional Study in Burera District.

作者信息

Maine Rebecca G, Linden Allison F, Riviello Robert, Kamanzi Emmanuel, Mody Gita N, Ntakiyiruta Georges, Kansayisa Grace, Ntaganda Edmond, Niyonkuru Francine, Mubiligi Joel M, Mpunga Tharcisse, Meara John G, Hedt-Gauthier Bethany L

机构信息

Department of Surgery, Harborview Medical Center, Seattle, Washington.

Now with Department of Surgery, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

出版信息

JAMA Surg. 2017 Dec 20;152(12):e174013. doi: 10.1001/jamasurg.2017.4013.

Abstract

IMPORTANCE

In low- and middle-income countries, community-level surgical epidemiology is largely undefined. Accurate community-level surgical epidemiology is necessary for surgical health systems planning.

OBJECTIVE

To determine the prevalence of surgical conditions in Burera District, Northern Province, Rwanda.

DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional study with a 2-stage cluster sample design (at village and household level) was carried out in Burera District in March and May 2012. A team of surgeons randomly sampled 30 villages with probability proportionate to village population size, then sampled 23 households within each village. All available household members were examined.

MAIN OUTCOMES AND MEASURES

The presence of 10 index surgical conditions (injuries/wounds, hernias/hydroceles, breast masses, neck masses, obstetric fistulas, undescended testes, hypospadias, hydrocephalus, cleft lip/palate, and clubfoot) was determined by physical examination. Prevalence was estimated overall and for each condition. Multivariable logistic regression was performed to identify factors associated with surgical conditions, accounting for the complex survey design.

RESULTS

Of the 2165 examined individuals, 1215 (56.2%) were female. The prevalence of any surgical condition among all examined individuals was 12% (95% CI, 9.2-14.9%). Half of conditions were hernias/hydroceles (49.6%), and 44% were injuries/wounds. In multivariable analysis, children 5 years or younger had twice the odds of having a surgical condition compared with married individuals 21 to 35 years of age (reference group) (odds ratio [OR], 2.2; 95% CI, 1.26-4.04; P = .01). The oldest group, people older than 50 years, also had twice the odds of having a surgical condition compared with the reference group (married, aged >50 years: OR, 2.3; 95% CI, 1.28-4.23; P = .01; unmarried, aged >50 years: OR, 2.38; 95% CI, 1.02-5.52; P = .06). Unmarried individuals 21 to 35 years of age and unmarried individuals aged 36 to 50 years had higher odds of a surgical condition compared with the reference group (aged 21-35 years: OR, 1.68; 95% CI, 0.74-3.82; P = .22; aged 36-50 years: OR, 3.35; 95% CI, 1.29-9.11; P = .02). There was no statistical difference in odds by sex, wealth, education, or travel time to the nearest hospital.

CONCLUSIONS AND RELEVANCE

The prevalence of surgically treatable conditions in northern Rwanda was considerably higher than previously estimated modeling and surveys in comparable low- and middle-income countries. This surgical backlog must be addressed in health system plans to increase surgical infrastructure and workforce in rural Africa.

摘要

重要性

在低收入和中等收入国家,社区层面的外科流行病学在很大程度上尚不明确。准确的社区层面外科流行病学对于外科卫生系统规划而言是必要的。

目的

确定卢旺达北部省布雷拉区外科疾病的患病率。

设计、地点和参与者:2012年3月和5月在布雷拉区开展了一项采用两阶段整群抽样设计(在村庄和家庭层面)的横断面研究。一组外科医生按照与村庄人口规模成比例的概率随机抽取了30个村庄,然后在每个村庄内抽取23户家庭。对所有能找到的家庭成员进行了检查。

主要结局和测量指标

通过体格检查确定10种指标外科疾病(损伤/伤口、疝/鞘膜积液、乳腺肿块、颈部肿块、产科瘘、隐睾、尿道下裂、脑积水、唇腭裂和马蹄内翻足)的存在情况。总体及每种疾病的患病率均进行了估算。进行多变量逻辑回归以识别与外科疾病相关的因素,同时考虑到复杂的调查设计。

结果

在2165名接受检查的个体中,1215名(56.2%)为女性。所有接受检查个体中任何外科疾病的患病率为12%(95%置信区间,9.2 - 14.9%)。一半的疾病为疝/鞘膜积液(49.6%),44%为损伤/伤口。在多变量分析中,5岁及以下儿童患外科疾病的几率是21至35岁已婚个体(参照组)的两倍(优势比[OR],2.2;95%置信区间,1.26 - 4.04;P = 0.01)。年龄最大的组,即50岁以上人群,患外科疾病的几率也是参照组的两倍(已婚,年龄>50岁:OR,2.3;95%置信区间,1.28 - 4.23;P = 0.01;未婚,年龄>50岁:OR,2.38;95%置信区间,1.02 - 5.52;P = 0.06)。21至35岁未婚个体和36至50岁未婚个体患外科疾病的几率高于参照组(年龄21 - 35岁:OR,1.68;95%置信区间,0.74 - 3.82;P = 0.22;年龄36 - 50岁:OR,3.35;95%置信区间,1.29 - 9.11;P = 0.02)。在患病几率方面,按性别、财富、教育程度或到最近医院的出行时间划分无统计学差异。

结论及意义

卢旺达北部可通过外科治疗的疾病患病率显著高于此前在类似低收入和中等收入国家进行的建模及调查所估计的水平。在卫生系统规划中必须解决这一外科积压问题,以增加非洲农村地区的外科基础设施和劳动力。

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