Miyakawa T, Katsuragi S, Kuramoto R
Department of Neuropsychiatry, Kumamoto University Medical School, Japan.
Virchows Arch B Cell Pathol Incl Mol Pathol. 1988;56(1):21-4. doi: 10.1007/BF02889997.
Perivascular amyloid fibrils in the brains of patients with Alzheimer's disease have been examined by electron microscopy. The amyloid fibrils showed a hollow rod structure and consisted of globular substances. Each turn appeared to be composed of five globular subunits. These findings coincide with the ultrastructure of amyloid fibrils obtained from replicas made by a rapid freezing method.
已通过电子显微镜检查了阿尔茨海默病患者大脑中的血管周围淀粉样纤维。淀粉样纤维呈空心杆状结构，由球状物质组成。每一圈似乎由五个球状亚基组成。这些发现与通过快速冷冻法制备的复制品中获得的淀粉样纤维的超微结构一致。
