Gao Yan, Lu Gang, Wang Ya-Yuan, Chen Li, Chen Rui, Liang Feng-Xia
College of Acupuncture-Moxibustion and Orthopaedics, Hubei University of Chinese Medicine/Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Wuhan 430061, China.
Integrated Traditional Chinese Medicine and Western Medicine Department, Union Hospital Affiliated to Tongji Medical College of Huazhong Science and Technology University, Wuhan 430022.
Zhen Ci Yan Jiu. 2017 Aug 25;42(4):367-71.
Diabetic gastroparesis (DGP) is an important complication of diabetes, and seriously impacts the patient's quality of life. In the present paper, the authors summarize national and international research on the mechanism of acupuncture therapy in improving DGP and the pathogenesis of DGP over the past 10 years. The authors illustrate the mechanism of acupuncture underlying the improvement in DGP as follows:1) the effect on autonomic nerves and neurons of the central nervous system; 2) promoting restoration of the enteric nervous system; 3) the effect on Cajal interstitial cells; 4) improving gastrointestinal hormone disorder; 5) improving hyperglycemic state; 6) the effect on gastric smooth muscle. The authors also put forward some suggestions for future research on the mechanisms of acupuncture in DGP.
糖尿病胃轻瘫（DGP）是糖尿病的一种重要并发症，严重影响患者的生活质量。在本文中，作者总结了过去10年国内外关于针刺疗法改善DGP的机制以及DGP发病机制的研究。作者阐述针刺改善DGP的机制如下：1）对自主神经和中枢神经系统神经元的作用；2）促进肠神经系统的恢复；3）对Cajal间质细胞的作用；4）改善胃肠激素紊乱；5）改善高血糖状态；6）对胃平滑肌的作用。作者还对未来针刺治疗DGP机制的研究提出了一些建议。
