自闭症谱系障碍和智力残疾中的自我伤害行为：探索对疼痛和感觉输入的反应性所起的作用。
Self-Injury in Autism Spectrum Disorder and Intellectual Disability: Exploring the Role of Reactivity to Pain and Sensory Input.
作者信息
Summers Jane, Shahrami Ali, Cali Stefanie, D'Mello Chantelle, Kako Milena, Palikucin-Reljin Andjelka, Savage Melissa, Shaw Olivia, Lunsky Yona
机构信息
Department of Psychiatry, University of Toronto, Toronto, ON M5S 1A1, Canada.
Centre for Addiction and Mental Health, 1001 Queen Street W, Toronto, ON M6J 1H4, Canada.
出版信息
Brain Sci. 2017 Oct 26;7(11):140. doi: 10.3390/brainsci7110140.
Abstract
This paper provides information about the prevalence and topography of self-injurious behavior in children and adults with autism spectrum disorder and intellectual disability. Dominant models regarding the etiology of self-injury in this population are reviewed, with a focus on the role of reactivity to pain and sensory input. Neuroimaging studies are presented and suggestions are offered for future research.
摘要
本文提供了有关自闭症谱系障碍和智力残疾儿童及成人自伤行为的患病率和部位的信息。本文回顾了关于该人群自伤行为病因的主要模型，重点关注对疼痛和感觉输入的反应性的作用。展示了神经影像学研究，并为未来研究提供了建议。
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本文引用的文献
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The Developmental Trajectory of Self-Injurious Behaviours in Individuals with Prader Willi Syndrome, Autism Spectrum Disorder and Intellectual Disability.普拉德-威利综合征、自闭症谱系障碍和智力残疾个体自我伤害行为的发展轨迹
Diseases. 2016 Feb 6;4(1):9. doi: 10.3390/diseases4010009.
2
Initially intact neural responses to pain in autism are diminished during sustained pain.自闭症患者在持续疼痛期间，其对疼痛的初始完整神经反应会减弱。
Autism. 2018 Aug;22(6):669-683. doi: 10.1177/1362361317696043. Epub 2017 May 17.
3
Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder.自闭症谱系障碍风险婴儿中自伤行为发展的潜在风险因素。
J Autism Dev Disord. 2017 May;47(5):1403-1415. doi: 10.1007/s10803-017-3057-9.
4
Neuroimaging chronic pain: what have we learned and where are we going?神经影像学与慢性疼痛：我们学到了什么，又将何去何从？
Future Neurol. 2014 Nov;9(6):615-626. doi: 10.2217/FNL.14.57.
5
Daily living pain assessment in children with autism: Exploratory study.自闭症儿童日常生活疼痛评估：探索性研究。
Res Dev Disabil. 2017 Mar;62:238-246. doi: 10.1016/j.ridd.2017.01.003. Epub 2017 Jan 13.
6
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J Autism Dev Disord. 2017 Mar;47(3):701-713. doi: 10.1007/s10803-016-3000-5.
7
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Autism. 2017 May;21(4):412-422. doi: 10.1177/1362361316644731. Epub 2016 May 12.
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