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成功策略:一项关于机器人辅助部分肾切除术治疗复杂肾脏病变的多机构研究。

Strategies for success: a multi-institutional study on robot-assisted partial nephrectomy for complex renal lesions.

机构信息

Department of Surgery, Austin Health, University of Melbourne, Melbourne, Vic., Australia.

Division of Cancer Surgery, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, Vic., Australia.

出版信息

BJU Int. 2018 May;121 Suppl 3:40-47. doi: 10.1111/bju.14059. Epub 2017 Dec 21.

Abstract

OBJECTIVE

To describe our technique, illustrated with images and videos, of robot-assisted partial nephrectomy (RAPN) for challenging renal tumours.

PATIENTS AND METHODS

A study of 249 patients who underwent RAPN in multiple institutions was performed. Patients were identified using prospective RAPN databases. Complex renal lesion were defined as those with a RENAL nephrometry score ≥10. Data were analysed and differences among groups examined.

RESULTS

A total of 31 (12.4%) RAPNs were performed for complex renal tumours. The median (interquartile range [IQR]) patient age was 57 (50.5-70.5) years and 21 patients (67.7%) were men. The median (IQR) American Society of Anesthesiologists score was 2 (2-3). The median (IQR) operating time was 200 (50-265) min, warm ischaemia time was 23 (18.5-29) min, and estimated blood loss was 200 (50-265) mL. There were no intra-operative complications. Two patients (6.4%) had postoperative complications. One patient (3.2%) had a positive surgical margin. The median (IQR) length of stay was 3.5 (3-5) days and the median (IQR) follow-up was 12.5 (7-24) months. There were no recurrences. RAPN resulted in statistically significant changes in renal function 3 months after RAPN compared with preoperative renal function (P < 0.001).

CONCLUSION

Our results showed that RAPN was a safe approach for selected patients with complex renal tumours and may facilitate tumour resection and renorrhaphy for challenging cases, offering a minimally invasive surgical option for patients who may otherwise require open surgery.

摘要

目的

通过图片和视频描述我们在多中心开展的机器人辅助部分肾切除术(RAPN)治疗复杂肾肿瘤的技术。

患者与方法

对多家医疗机构开展的 249 例行 RAPN 患者进行了研究。通过前瞻性 RAPN 数据库识别患者。复杂肾病变定义为 RENAL 肾肿瘤评分≥10 的患者。分析数据并检查组间差异。

结果

共 31 例(12.4%)RAPN 用于治疗复杂肾肿瘤。患者年龄中位数(四分位距 [IQR])为 57 岁(50.5-70.5),21 例(67.7%)为男性。美国麻醉医师协会评分中位数(IQR)为 2 分(2-3 分)。手术时间中位数(IQR)为 200 分钟(50-265 分钟),热缺血时间中位数(IQR)为 23 分钟(18.5-29 分钟),估计失血量为 200 毫升(50-265 毫升)。无术中并发症。2 例(6.4%)术后发生并发症。1 例(3.2%)患者切缘阳性。中位住院时间(IQR)为 3.5 天(3-5 天),中位随访时间(IQR)为 12.5 个月(7-24 个月)。无复发。RAPN 后 3 个月与术前肾功能相比,肾功能有统计学显著变化(P<0.001)。

结论

我们的研究结果表明,RAPN 是治疗复杂肾肿瘤患者的一种安全方法,可为挑战性病例提供肿瘤切除和肾缝合,为可能需要开放性手术的患者提供微创外科选择。

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