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Reply to Dorrington et al. and to Swenson: "Hypercapnic Pulmonary Vasoconstriction Contributes to Regional Perfusion Distribution: Relevance to Asthma" and "Hypercapnic Pulmonary Vasoconstriction as a Mechanism for Regional Perfusion Redistribution in Asthma".

作者信息

Kelly Vanessa J, Winkler Tilo, Harris R Scott

机构信息

1 Harvard Medical School Boston, Massachusetts.

出版信息

Am J Respir Crit Care Med. 2018 Mar 1;197(5):684. doi: 10.1164/rccm.201709-1892LE.

DOI:10.1164/rccm.201709-1892LE
PMID:29072850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6005244/
Abstract
摘要

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1
Reply to Dorrington et al. and to Swenson: "Hypercapnic Pulmonary Vasoconstriction Contributes to Regional Perfusion Distribution: Relevance to Asthma" and "Hypercapnic Pulmonary Vasoconstriction as a Mechanism for Regional Perfusion Redistribution in Asthma".回复多林顿等人及斯文森：《高碳酸血症性肺血管收缩对区域灌注分布的影响：与哮喘的相关性》及《高碳酸血症性肺血管收缩作为哮喘区域灌注再分布的一种机制》
Am J Respir Crit Care Med. 2018 Mar 1;197(5):684. doi: 10.1164/rccm.201709-1892LE.
2
Hypercapnic Pulmonary Vasoconstriction Contributes to Regional Perfusion Distribution: Relevance to Asthma.高碳酸血症性肺血管收缩对区域灌注分布有影响：与哮喘的相关性。
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Comparison of the effects of nicorandil, pinacidil and nitroglycerin on hypoxic and hypercapnic pulmonary vasoconstriction in the isolated perfused lung of rat.尼可地尔、匹那地尔和硝酸甘油对大鼠离体灌注肺缺氧和高碳酸血症性肺血管收缩作用的比较。
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本文引用的文献

1
Hypoxic Pulmonary Vasoconstriction Does Not Explain All Regional Perfusion Redistribution in Asthma.低氧性肺血管收缩并不能解释哮喘中所有的区域灌注再分布。
Am J Respir Crit Care Med. 2017 Oct 1;196(7):834-844. doi: 10.1164/rccm.201612-2438OC.
2
Pulmonary gas exchange responses to histamine and methacholine challenges in mild asthma.轻度哮喘患者对组胺和乙酰甲胆碱激发试验的肺气体交换反应
Eur Respir J. 2001 Apr;17(4):609-14. doi: 10.1183/09031936.01.17406090.
3
Local pulmonary blood flow: control and gas exchange.局部肺血流：调控与气体交换
Respir Physiol. 1993 Oct;94(1):91-107. doi: 10.1016/0034-5687(93)90059-j.
4
The effect of PCO2 on hypoxic pulmonary vasoconstriction.二氧化碳分压对低氧性肺血管收缩的影响。
Can Anaesth Soc J. 1981 Sep;28(5):422-30. doi: 10.1007/BF03010350.
5
CO2 and mechanical factors reduce blood flow in a collapsed lung lobe.二氧化碳和机械因素会减少萎陷肺叶的血流。
J Appl Physiol Respir Environ Exerc Physiol. 1984 Sep;57(3):739-43. doi: 10.1152/jappl.1984.57.3.739.
6
Arterial-blood gas tension in asthma.哮喘患者的动脉血气张力
N Engl J Med. 1968 May 9;278(19):1027-32. doi: 10.1056/NEJM196805092781901.
7
Stimulus-response curves for the pulmonary vascular bed to hypoxia and hypercapnia.肺血管床对低氧和高碳酸血症的刺激-反应曲线。
J Physiol. 1970 Nov;211(1):139-55. doi: 10.1113/jphysiol.1970.sp009271.
8
Arterial blood gases in bronchial asthma.支气管哮喘的动脉血气分析
J Allergy. 1970 Apr;45(4):248-54. doi: 10.1016/0021-8707(70)90135-8.
9
Assessing acid-base status in circulatory failure. Differences between arterial and central venous blood.评估循环衰竭时的酸碱状态。动脉血与中心静脉血的差异。
N Engl J Med. 1989 May 18;320(20):1312-6. doi: 10.1056/NEJM198905183202004.