Bioconjug Chem. 2018 Mar 21;29(3):709-718. doi: 10.1021/acs.bioconjchem.7b00563. Epub 2017 Nov 7.
In 2015, cancer was the cause of almost 22% of deaths worldwide. The high frequency of relapsing diseases and metastasis requires the development of new diagnostic and therapeutic approaches, and the use of nanomaterials is a promising tool for fighting cancer. Among the more extensively studied nanomaterials are carbon nanotubes (CNTs), synthesized as graphene sheets, whose spiral shape is varied in length and thickness. Their physicochemical features, such as the resistance to tension, and thermal and electrical conductivity, allow their application in several fields. In this review, we show evidence supporting the applicability of CNTs in biomedical practice as nanocarriers for drugs and immunomodulatory material, emphasizing their potential for use in cancer treatment.
2015 年,癌症是全球近 22%死亡人数的主要原因。疾病复发和转移的高频率要求开发新的诊断和治疗方法,而纳米材料的使用是对抗癌症的有前途的工具。在更广泛研究的纳米材料中,有碳纳米管(CNTs),它们被合成成为石墨烯片,其螺旋形状在长度和厚度上有所不同。它们的物理化学特性,如抗张强度、热导率和电导率,允许它们在多个领域应用。在这篇综述中,我们展示了支持 CNTs 作为药物和免疫调节材料的纳米载体在生物医学实践中的适用性的证据,强调了它们在癌症治疗中的潜在用途。