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Effects of ketanserin and 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monohydrochloride (SGB-1534), anti-hypertensive agents, on 3H-serotonin and 3H-ketanserin bindings to serotonergic (5HT1 and 5HT2) receptors in dog brain and aorta.

作者信息

Nagatomo T, Hokibara R, Tanaka Y, Nakamura T, Aono J, Tsuchihashi H

出版信息

Chem Pharm Bull (Tokyo). 1988 Aug;36(8):3113-8. doi: 10.1248/cpb.36.3113.

DOI:10.1248/cpb.36.3113
PMID:2907307
Abstract
摘要

相似文献

1
Effects of ketanserin and 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monohydrochloride (SGB-1534), anti-hypertensive agents, on 3H-serotonin and 3H-ketanserin bindings to serotonergic (5HT1 and 5HT2) receptors in dog brain and aorta.降压药酮色林和3-[2-[4-(邻甲氧基苯基)-1-哌嗪基]乙基]-2,4(1H,3H)-喹唑啉二酮单盐酸盐(SGB-1534)对犬脑和主动脉中3H-5-羟色胺及3H-酮色林与5-羟色胺能(5HT1和5HT2)受体结合的影响。
Chem Pharm Bull (Tokyo). 1988 Aug;36(8):3113-8. doi: 10.1248/cpb.36.3113.
2
Effect of 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monophydrochloride (SGB-1534), an antihypertensive agent, on 3H-prazosin and 3H-p-aminoclonidine binding to alpha 1- and alpha 2-adrenoceptors in dog brain and aorta.抗高血压药3-[2-[4-(邻甲氧基苯基)-1-哌嗪基]乙基]-2,4(1H,3H)-喹唑啉二酮单盐酸盐(SGB-1534)对3H-哌唑嗪和3H-对氨基可乐定与犬脑和主动脉中α1和α2肾上腺素能受体结合的影响。
Chem Pharm Bull (Tokyo). 1988 Mar;36(3):1122-7. doi: 10.1248/cpb.36.1122.
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MCI-9042: high affinity for serotonergic receptors as assessed by radioligand binding assay.MCI - 9042:通过放射性配体结合试验评估,对血清素能受体具有高亲和力。
J Pharmacobiodyn. 1991 Apr;14(4):177-81. doi: 10.1248/bpb1978.14.177.
4
Mechanism of the hypotensive effect of a novel phenylpiperazine derivative, SGB-1534: antagonism at alpha 1-adrenergic and 5-HT2 receptors.新型苯基哌嗪衍生物SGB-1534的降压作用机制:对α1-肾上腺素能受体和5-HT2受体的拮抗作用
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Binding characteristics of [3H]ketanserin for serotonin-2 receptor in the rabbit platelet.[3H]酮色林与兔血小板中血清素-2受体的结合特性
J Pharmacobiodyn. 1991 Aug;14(8):461-6. doi: 10.1248/bpb1978.14.461.
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Effects of a new antihypertensive agent, SGB-1534, on rat platelet aggregation.新型抗高血压药物SGB - 1534对大鼠血小板聚集的影响。
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Comparison of the effect of irindalone, a novel serotonin 5-HT2 antagonist and ketanserin on mechanical responses of rat thoracic aorta.
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A comparison of 5-hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists.介导兔主动脉和犬隐静脉收缩的5-羟色胺受体比较:使用选择性激动剂和拮抗剂获得不同受体类型的证据。
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J Cardiovasc Pharmacol. 1985;7 Suppl 7:S2-11. doi: 10.1097/00005344-198500077-00002.