Patel Jaymin C, George Josiah, Vuong Jeni, Potts Caelin C, Bozio Catherine, Clark Thomas A, Thomas Jerry, Schier Joshua, Chang Arthur, Waller Jessica L, Diaz Maureen H, Whaley Melissa, Jenkins Laurel T, Fuller Serena, Williams Desmond E, Redd John T, Arthur Ray R, Taweh Fahn, Vera Walker Yatta, Hardy Patrick, Freeman Maxwell, Katawera Victoria, Gwesa Gulu, Gbanya Miatta Z, Clement Peter, Kohar Henry, Stone Mardia, Fallah Mosoka, Nyenswah Tolbert, Winchell Jonas M, Wang Xin, McNamara Lucy A, Dokubo E Kainne, Fox LeAnne M
MMWR Morb Mortal Wkly Rep. 2017 Oct 27;66(42):1144-1147. doi: 10.15585/mmwr.mm6642a5.
On April 25, 2017, a cluster of unexplained illness and deaths among persons who had attended a funeral during April 21-22 was reported in Sinoe County, Liberia (1). Using a broad initial case definition, 31 cases were identified, including 13 (42%) deaths. Twenty-seven cases were from Sinoe County (1), and two cases each were from Grand Bassa and Monsterrado counties, respectively. On May 5, 2017, initial multipathogen testing of specimens from four fatal cases using the Taqman Array Card (TAC) assay identified Neisseria meningitidis in all specimens. Subsequent testing using direct real-time polymerase chain reaction (PCR) confirmed N. meningitidis in 14 (58%) of 24 patients with available specimens and identified N. meningitidis serogroup C (NmC) in 13 (54%) patients. N. meningitidis was detected in specimens from 11 of the 13 patients who died; no specimens were available from the other two fatal cases. On May 16, 2017, the National Public Health Institute of Liberia and the Ministry of Health of Liberia issued a press release confirming serogroup C meningococcal disease as the cause of this outbreak in Liberia.
2017年4月25日，利比里亚锡诺埃县报告了一起在4月21 - 22日参加葬礼的人群中出现的不明病因疾病和死亡聚集性事件（1）。采用宽泛的初始病例定义，共识别出31例病例，其中13例（42%）死亡。27例来自锡诺埃县（1），大巴萨县和蒙特塞拉多县各有2例。2017年5月5日，使用Taqman Array Card（TAC）检测法对4例死亡病例的标本进行的初步多病原体检测在所有标本中均检出脑膜炎奈瑟菌。随后使用直接实时聚合酶链反应（PCR）检测，在24例有可用标本的患者中，14例（58%）确诊为脑膜炎奈瑟菌感染，13例（54%）患者鉴定为C群脑膜炎奈瑟菌（NmC）。在13例死亡患者中的11例标本中检测到脑膜炎奈瑟菌；另外2例死亡病例没有可用标本。2017年5月16日，利比里亚国家公共卫生研究所和利比里亚卫生部发布新闻稿，确认C群脑膜炎球菌病是利比里亚此次疫情的病因。
