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尼日利亚北部扎里亚的脑膜炎球菌感染疫情。1. 一般流行病学特征。

An epidemic of meningococcal infection at Zaria, Northern Nigeria. 1. General epidemiological features.

作者信息

Greenwood B M, Bradley A K, Cleland P G, Haggie M H, Hassan-King M, Lewis L S, Macfarlane J T, Taqi A, Whittle H C, Bradley-Moore A M, Ansari Q

出版信息

Trans R Soc Trop Med Hyg. 1979;73(5):557-62. doi: 10.1016/0035-9203(79)90052-x.

Abstract

In 1977 Zaria, in Northern Nigeria, was affected by a severe epidemic of group A meningococcal infection, 1,257 patients being admitted to hospital with the disease during a three-month period. The epidemic started towards the end of the dry season when it was hot, dry and dusty and finished shortly after the onset of the rains. The over-all attack rate was 3.6 per 1,000 but this varied considerably from area to area within the town. Few cases occurred amongst those belonging to the upper social classes. The disease was seen most frequently amongst those from five to 14 years old and there was a strong male preponderance. The over-all mortality was 8.3% but mortality was much higher (40.6%) amongst 67 patients with acute meningococcaemia.

摘要

1977年,尼日利亚北部的扎里亚遭受了A群脑膜炎球菌感染的严重疫情,在三个月的时间里,有1257名该疾病患者入院治疗。疫情始于旱季末期,当时天气炎热、干燥且多尘,在雨季开始后不久结束。总体发病率为每1000人中有3.6例,但在城镇内不同区域差异很大。上层社会阶层中很少有病例发生。该疾病在5至14岁的人群中最为常见,且男性占比很大。总体死亡率为8.3%,但在67例急性脑膜炎球菌血症患者中,死亡率要高得多(40.6%)。

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