Tammisto T, Paloheimo M, Linko K, Wirtavuori K
Department of Anaesthesia, Helsinki University Central Hospital, Finland.
Eur J Anaesthesiol. 1988 Nov;5(6):361-7.
The behaviour of spontaneous frontal electromyographic activity (FEMG) was studied during the recovery from suxamethonium and vecuronium block. In order to obtain comparable conditions in the study groups, the duration of the suxamethonium block was prolonged with a suxamethonium infusion. The FEMG was continuously recorded and the evoked electromyographic (EEMG) and twitch tension (ETT) responses were measured every 10 s from the thenar muscles. The median FEMG remained at the base level in 8 of the 12 vecuronium patients, despite a 50% recovery of EEMG. In the suxamethonium group there was an increase in FEMG in all six patients when EEMG had recovered to 10%, and significantly higher FEMG readings were obtained during further recovery from the block. Thus, early recovery of neuromuscular transmission is detected by FEMG more easily when suxamethonium is used instead of vecuronium. The different behaviour of FEMG may reflect a difference in the recovery ratio of ETT/EEMG or in the anaesthetic depth caused by the two types of neuromuscular blockers.
在琥珀胆碱和维库溴铵阻滞恢复过程中，对自发性额肌电图活动（FEMG）的行为进行了研究。为了在研究组中获得可比条件，通过输注琥珀胆碱延长了琥珀胆碱阻滞的持续时间。持续记录FEMG，并每隔10秒测量一次来自大鱼际肌的诱发肌电图（EEMG）和抽搐张力（ETT）反应。12例维库溴铵患者中有8例的FEMG中位数保持在基础水平，尽管EEMG恢复了50%。在琥珀胆碱组中，当EEMG恢复到10%时，所有6例患者的FEMG均增加，并且在阻滞进一步恢复期间获得了显著更高的FEMG读数。因此，当使用琥珀胆碱而非维库溴铵时，FEMG更容易检测到神经肌肉传递的早期恢复。FEMG的不同行为可能反映了ETT/EEMG恢复率的差异或两种类型的神经肌肉阻滞剂引起的麻醉深度的差异。
