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成年住院患者外周静脉导管使用结果的观察性研究:外周静脉导管失败的多变量分析

Observational Study of Peripheral Intravenous Catheter Outcomes in Adult Hospitalized Patients: A Multivariable Analysis of Peripheral Intravenous Catheter Failure.

作者信息

Marsh Nicole, Webster Joan, Larson Emily, Cooke Marle, Mihala Gabor, Rickard Claire M

机构信息

1Nursing & Midwifery Research Centre, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

School of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia.

出版信息

J Hosp Med. 2018 Feb 1;13(2):83-89. doi: 10.12788/jhm.2867. Epub 2017 Oct 18.

DOI:10.12788/jhm.2867
PMID:29073316
Abstract

BACKGROUND

Almost 70% of hospitalized patients require a peripheral intravenous catheter (PIV), yet up to 69% of PIVs fail prior to completion of therapy.

OBJECTIVE

To identify risk factors associated with PIV failure.

DESIGN

A single center, prospective, cohort study.

SETTING

Medical and surgical wards of a tertiary hospital located in Queensland, Australia.

PARTICIPANTS

Adult patients requiring a PIV.

MEASUREMENTS

Demographic, clinical, and potential PIV risk factors were collected. Failure occurred if the catheter had complications at removal.

RESULTS

We recruited 1000 patients. Catheter failure occurred in 512 (32%) of 1578 PIVs. Occlusion/infiltration risk factors included intravenous (IV) flucloxacillin (hazard ratio [HR], 1.98; 95% confidence interval [CI], 1.19-3.31), 22-gauge PIVs (HR, 1.43; 95% CI, 1.02-2.00), and female patients (HR, 1.48; 95% CI, 1.10-2.00). Phlebitis was associated with female patients (HR, 1.81; 95% CI, 1.40-2.35), bruised insertion sites (HR, 2.16; 95% CI, 1.26-3.71), IV flucloxacillin (HR, 2.01; 95% CI, 1.26-3.21), and dominant side insertion (HR, 1.39; 95% CI, 1.09-1.77). Dislodgement risks were a paramedic insertion (HR, 1.78; 95% CI, 1.03-3.06).Each increase by 1 in the average number of daily PIV accesses was associated (HR 1.11, 95% CI 1.03-1.20)-(HR 1.14, 95% CI 1.08-1.21) with occlusion/infiltration, phlebitis and dislodgement. Additional securement products were associated with less (HR 0.32, 95% C-0.46)-(HR 0.63, 95% CI 0.48-0.82) occlusion/infiltration, phlebitis and dislodgement.

CONCLUSION

Modifiable risk factors should inform education and inserter skill development to reduce the currently high rate of PIV failure.

摘要

背景

近70%的住院患者需要外周静脉导管(PIV),然而高达69%的PIV在治疗完成前失败。

目的

确定与PIV失败相关的风险因素。

设计

单中心前瞻性队列研究。

地点

位于澳大利亚昆士兰州的一家三级医院的内科和外科病房。

参与者

需要PIV的成年患者。

测量

收集人口统计学、临床和潜在的PIV风险因素。如果导管在拔除时有并发症则判定为失败。

结果

我们招募了1000名患者。1578根PIV中有512根(32%)发生导管失败。堵塞/渗漏的风险因素包括静脉输注氟氯西林(风险比[HR],1.98;95%置信区间[CI],1.19 - 3.31)、22号PIV(HR,1.43;95% CI,1.02 - 2.00)以及女性患者(HR,1.48;95% CI,1.10 - 2.00)。静脉炎与女性患者(HR,1.81;95% CI,1.40 - 2.35)、穿刺部位瘀青(HR,2.16;95% CI,1.26 - 3.71)、静脉输注氟氯西林(HR,2.01;95% CI,1.26 - 3.21)以及优势侧穿刺(HR,1.39;95% CI,1.09 - 1.77)有关。脱出风险是由护理人员穿刺(HR,1.78;95% CI,1.03 - 3.06)。每日PIV穿刺平均次数每增加1次,与堵塞/渗漏、静脉炎和脱出相关(HR 1.11,95% CI 1.03 - 1.20) - (HR 1.14,95% CI 1.08 - 1.21)。额外的固定产品与较少的堵塞/渗漏、静脉炎和脱出相关(HR 0.32,95% CI 【此处原文似乎有误,推测可能是0.46 - 0.63】) - (HR 0.63,95% CI 0.48 - 0.82)。

结论

可改变的风险因素应指导教育和穿刺者技能培养,以降低目前PIV的高失败率。

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