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本文引用的文献

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Antibiotic-associated psychosis during treatment of urinary tract infections: a systematic review.尿路感染治疗期间的抗生素相关性精神病：一项系统综述
J Clin Psychopharmacol. 2014 Aug;34(4):483-90. doi: 10.1097/JCP.0000000000000150.
2
Ciprofloxacin-induced psychosis.环丙沙星所致精神病
J Neuropsychiatry Clin Neurosci. 2014 Winter;26(1):E36-7. doi: 10.1176/appi.neuropsych.13020033.
3
Ofloxacin-induced hallucinations.氧氟沙星致幻觉。
Indian J Pharmacol. 2013 Mar-Apr;45(2):189-90. doi: 10.4103/0253-7613.108316.
4
Quinolones: review of psychiatric and neurological adverse reactions.喹诺酮类药物：精神和神经系统不良反应综述。
Drug Saf. 2011 Jun 1;34(6):465-88. doi: 10.2165/11587280-000000000-00000.
5
Organic psychosis induced by ofloxacin and metronidazole.由氧氟沙星和甲硝唑引起的器质性精神病。
Br J Hosp Med (Lond). 2009 Apr;70(4):236-7. doi: 10.12968/hmed.2009.70.4.41632.
6
Levofloxacin-induced delirium.左氧氟沙星所致谵妄
Neurol Sci. 2009 Apr;30(2):159-61. doi: 10.1007/s10072-009-0027-9. Epub 2009 Feb 3.
7
Levofloxacin-induced delirium with psychotic features.左氧氟沙星诱发的伴有精神病性症状的谵妄。
Gen Hosp Psychiatry. 2008 Jul-Aug;30(4):381-3. doi: 10.1016/j.genhosppsych.2007.11.003.
8
Delirium associated with gatifloxacin.加替沙星相关性谵妄
Psychosomatics. 2003 Jan-Feb;44(1):85-6. doi: 10.1176/appi.psy.44.1.85.
9
Fluoroquinolone toxicity profiles: a review focusing on newer agents.氟喹诺酮类药物的毒性概况：聚焦新型药物的综述
Clin Infect Dis. 1999 Feb;28(2):352-64. doi: 10.1086/515104.
10
Ciprofloxacin-induced delirium.环丙沙星所致谵妄。
Ann Pharmacother. 1997 Feb;31(2):252. doi: 10.1177/106002809703100221.

高剂量氧氟沙星致一名4岁儿童出现双峰性幻觉

High Dose Ofloxacin-induced Bimodal Hallucinations in a 4 Years Old Child.

作者信息

Bhattacharya Arnab, Sharan Rajiv, Praharaj Samir Kumar

机构信息

Department of Psychiatry, Tata Motors Hospital, Jamshedpur, India.

Department of Pediatrics, Tata Motors Hospital, Jamshedpur, India.

出版信息

Clin Psychopharmacol Neurosci. 2017 Nov 30;15(4):416-417. doi: 10.9758/cpn.2017.15.4.416.

DOI:10.9758/cpn.2017.15.4.416
PMID:29073756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5678492/
Abstract

Ofloxacin is a commonly used quinolone antibiotic both in adults as well as children. It is generally safe and well tolerated. Rarely, neurological and psychiatric adverse reactions are reported to occur with ofloxacin. We report a case of a child who developed delirium after ofloxacin treatment, that resolved after medication discontinuation and treatment with low dose olanzapine.

摘要

氧氟沙星是一种常用于成人和儿童的喹诺酮类抗生素。它通常安全且耐受性良好。据报道，氧氟沙星很少会引起神经和精神方面的不良反应。我们报告一例儿童在使用氧氟沙星治疗后出现谵妄，停药并使用小剂量奥氮平治疗后症状缓解。