Li Ti, Zhai Xiangkai, Song Feifei, Zhu Hongguang
a Department of Dentistry , People's Hospital of Weifang , Weifang , Shandong Province , P.R. China.
Acta Odontol Scand. 2018 Mar;76(2):135-140. doi: 10.1080/00016357.2017.1392602. Epub 2017 Oct 26.
Selective and non-selective methods for caries removal were controversial so far, thus we aimed to compare the efficacy of selective and non-selective caries removal by conducting meta-analysis of randomized controlled trials (RCTs).
Eligible RCTs studies comparing selective caries removal with non-selective caries removal were retrieved by searching PubMed, EMBASE and Cochrane Library till 15 July 2017. The pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for outcome indictors, including pulpal exposure, pulpal symptoms and failure using Inverse variance-random effects or Mantel-Haenszel-fixed effects models.
Totally, seven studies were eligible for the meta-analysis. Compared with the non-selective caries removal group, the risk of pulpal exposure was significantly reduced in the selective caries removal group (OR = 0.11, 95% CI: 0.04-0.30). No significant difference was observed in pulpal symptoms (OR = 0.79, 95% CI: 0.30-2.12) and failure (OR = 1.40, 95% CI: 0.69-2.84) between the groups.
The efficacy of selective caries removal appears comparable to that of non-selective caries removal in children, with similar pulpal symptoms and failure, but selective caries removal may result in a low incidence of pulpal exposure. However, larger-scale RCTs with long-term follow-up are required to confirm this conclusion.
迄今为止,选择性和非选择性龋病去除方法存在争议,因此我们旨在通过对随机对照试验(RCT)进行荟萃分析,比较选择性和非选择性龋病去除的疗效。
通过检索PubMed、EMBASE和Cochrane图书馆,检索截至2017年7月15日比较选择性龋病去除与非选择性龋病去除的合格RCT研究。使用逆方差随机效应或Mantel-Haenszel固定效应模型计算包括牙髓暴露、牙髓症状和失败在内的结局指标的合并比值比(OR)及其95%置信区间(CI)。
总共有7项研究符合荟萃分析的条件。与非选择性龋病去除组相比,选择性龋病去除组牙髓暴露的风险显著降低(OR = 0.11,95% CI:0.04 - 0.30)。两组之间在牙髓症状(OR = 0.79,95% CI:0.30 - 2.12)和失败(OR = 1.40,95% CI:0.69 - 2.84)方面未观察到显著差异。
在儿童中,选择性龋病去除的疗效似乎与非选择性龋病去除相当,牙髓症状和失败情况相似,但选择性龋病去除可能导致牙髓暴露的发生率较低。然而,需要更大规模的长期随访RCT来证实这一结论。