Choi Yoonyoung, Eworuke Efe, Segal Richard
Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, P.O. Box 100496, Gainesville, FL 32610, USA.
Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, P.O. Box 100496, Gainesville, FL 32610, USA; Division of Epidemiology II, Office of Surveillance and Epidemiology, Office of Pharmacovigilance and Epidemiology, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA.
Papillomavirus Res. 2016 Dec;2:46-51. doi: 10.1016/j.pvr.2016.02.001. Epub 2016 Mar 4.
To identify factors that explain differences in HPV vaccination rates for male and female adolescents and to determine self-reported barriers by parents affecting vaccination decisions.
The sample included adolescents 13-17 years old with a vaccination record documented in the 2012 and 2013 National Immunization Survey-Teen dataset. A logistic regression model was developed with 13 socio-demographic factors and survey year, along with significant interaction pairs with gender.
Subjects included 20,355 and 18,350 adolescent boys and girls, respectively. About half of the females (56%) received at least one dose of HPV vaccine, compared to 28% of males. Several factors differed between males and females, including higher vaccination rates among non-Hispanic Black males and lower vaccination rates for non-Hispanic Black females compared to Whites; and a stronger association with health care provider recommendation among males. The most common parental reasons for not vaccinating their children included 'not recommended by a health care provider' for males (24%), and 'unnecessary' for females (18%).
We found a significant gender interaction with several socio-demographic variables in predicting vaccination uptake. These gender differences may be partially an artifact of timing, because male vaccination became routine approximately five years after female vaccination.
确定能够解释青少年男性和女性人乳头瘤病毒（HPV）疫苗接种率差异的因素，并确定父母自我报告的影响疫苗接种决策的障碍。
样本包括13 - 17岁且在2012年和2013年全国青少年免疫调查数据集中有疫苗接种记录的青少年。构建了一个逻辑回归模型，纳入13个社会人口学因素、调查年份以及与性别显著相关的交互对。
研究对象分别包括20355名青少年男性和18350名青少年女性。约一半的女性（56%）接种了至少一剂HPV疫苗，而男性的这一比例为28%。男性和女性在几个因素上存在差异，包括非西班牙裔黑人男性的疫苗接种率高于白人，而非西班牙裔黑人女性的疫苗接种率低于白人；男性与医疗保健提供者的建议关联更强。父母不给孩子接种疫苗的最常见原因，男性为“医疗保健提供者不建议”（24%），女性为“不必要”（18%）。
我们发现在预测疫苗接种率方面，性别与几个社会人口学变量之间存在显著的交互作用。这些性别差异可能部分是由于时间因素，因为男性疫苗接种比女性疫苗接种大约晚五年才成为常规操作。
