Department of Chemical and Environmental Engineering, University of Oviedo, Julián Clavería 8, 33006 Oviedo, Spain; Department of Physical and Analytical Chemistry, University of Oviedo, Julián Clavería 8, 33006 Oviedo, Spain.
Department of Chemical and Environmental Engineering, University of Oviedo, Julián Clavería 8, 33006 Oviedo, Spain.
Trends Biotechnol. 2018 Jan;36(1):10-14. doi: 10.1016/j.tibtech.2017.10.005. Epub 2017 Oct 23.
Bionanotechnology routes have been recently developed to produce fully artificial exosomes: biomimetic particles designed to overcome certain limitations in extracellular vesicle (EV) biology and applications. These particles could soon become true therapeutic biomaterials. Here, we outline their current preparation techniques, their explored and future possibilities, and their present limits.
近年来，人们开发了生物纳米技术途径来生产完全人工的外泌体：仿生颗粒旨在克服细胞外囊泡 (EV) 生物学和应用中的某些限制。这些颗粒可能很快成为真正的治疗性生物材料。在这里，我们概述了它们目前的制备技术、已探索和未来的可能性以及目前的局限性。
