移植肿瘤模型中的发散进化轨迹。
Divergent evolutionary trajectories in transplanted tumor models.
机构信息
Liver Cancer Research Program, Division of Liver Diseases, Tisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Division of Hematology and Medical Oncology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
出版信息
Nat Genet. 2017 Oct 27;49(11):1565-1566. doi: 10.1038/ng.3983.
DOI:10.1038/ng.3983
PMID:29074950
Abstract
Human-derived tumor models are becoming popular in the context of personalized medicine, but a new study shows that these models could be less representative of primary tumors than previously thought, particularly when using late passages.
摘要
在个性化医学的背景下，人类来源的肿瘤模型越来越受欢迎，但一项新的研究表明，这些模型可能不如以前认为的那样能代表原发性肿瘤，特别是在使用晚期传代时。
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