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针对非裔美国子宫癌幸存者的健康生活方式干预:研究方案。

Healthy lifestyle intervention for African American uterine cancer survivors: Study protocol.

作者信息

Stewart Jessica Lynn, Besenyi Gina B, Williams Lovoria B, Burt Victoria, Anglin Judith C, Ghamande Sharad A, Coughlin Steven Scott

机构信息

Department of Clinical and Digital Health Sciences, College of Allied Health Sciences, Augusta University, Augusta, GA, United States.

College of Nursing, Biobehavioral Nursing Department, Augusta University, Augusta, GA, United States.

出版信息

Contemp Clin Trials Commun. 2017 Dec;8:11-17. doi: 10.1016/j.conctc.2017.08.011. Epub 2017 Aug 18.

Abstract

BACKGROUND

Cancer of the uterine corpus is the most common gynecologic malignancy and the fourth most common cancer in U.S. women. There is a racial disparity in the survival from endometrial cancer and this may be addressed by culturally-tailored lifestyle interventions to help African American (AA) endometrial cancer survivors lose weight or maintain a healthy weight.

OBJECTIVE

The overall purpose of this pilot study is to develop and evaluate a culturally-tailored lifestyle intervention to help AA uterine cancer survivors reduce their risk of cancer recurrence and improve their quality of life through healthy eating, physical activity, and weight management. While many interventions have been evaluated to assist cancer survivors through diet and physical activity, few have focused on AA women with a uterine cancer diagnosis.

METHODS

Community-engaged research principles are being followed. This study was developed with input from the Augusta University (AU) College of Nursing Community Advisory Board (CAB) and the Division of Gynecologic Oncology at the Georgia Cancer Center at AU. Weekly sessions throughout a 12-week intervention will include physical activity and lectures on improving nutritional status. The pre/post-test design includes baseline and 6-month follow-up, where participants will complete a questionnaire that assesses knowledge and attitudes about physical activity, nutrition, uterine cancer, social support, and quality of life.

CONCLUSIONS

From this pilot study, we will learn more about the feasibility and integration of healthy lifestyle interventions in this patient population, and the results can provide an opportunity for a larger-scale, multi-center study with a randomized controlled design.

摘要

背景

子宫体癌是最常见的妇科恶性肿瘤,在美国女性中是第四大常见癌症。子宫内膜癌患者的生存率存在种族差异,可通过针对不同文化背景定制的生活方式干预措施来解决这一问题,以帮助非裔美国(AA)子宫内膜癌幸存者减轻体重或保持健康体重。

目的

这项试点研究的总体目的是开发并评估一种针对不同文化背景定制的生活方式干预措施,以帮助AA子宫癌幸存者通过健康饮食、体育活动和体重管理来降低癌症复发风险并改善生活质量。虽然已经评估了许多通过饮食和体育活动来帮助癌症幸存者的干预措施,但很少有针对被诊断为子宫癌的AA女性的研究。

方法

遵循社区参与研究原则。本研究是在奥古斯塔大学(AU)护理学院社区咨询委员会(CAB)和AU佐治亚癌症中心妇科肿瘤学部门的参与下开展的。在为期12周的干预期间,每周的课程将包括体育活动以及关于改善营养状况的讲座。前后测试设计包括基线和6个月随访,参与者将完成一份问卷,评估其对体育活动、营养、子宫癌、社会支持和生活质量的知识和态度。

结论

通过这项试点研究,我们将更多地了解在该患者群体中实施健康生活方式干预措施的可行性和整合情况,研究结果可为开展更大规模的随机对照多中心研究提供契机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ac/5898471/93ea5be83c24/gr1.jpg

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