Department of Anesthesia, Carver College of Medicine, University of Iowa, Iowa City, USA.
Department of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, Iowa City, USA.
J Health Psychol. 2020 May;25(6):819-829. doi: 10.1177/1359105317736577. Epub 2017 Oct 27.
This study examined whether depression and anxiety differentially relate to fatigue, sleep disturbance, pain catastrophizing, fear of movement, and pain severity in women with fibromyalgia. Baseline data from the Fibromyalgia Activity Study with Transcutaneous Electrical Nerve Stimulation were analyzed. Of 191 participants, 50 percent reported high anxiety and/or depression (17% high anxiety, 9% high depression, and 24% both). Fatigue and sleep impairment were associated with high depression ( < 0.05). Pain severity, pain catastrophizing, and fear of movement were associated with high anxiety and high depression ( < 0.05). Possible implications for underlying mechanisms and the need for targeted treatments are discussed.
本研究旨在探讨在患有纤维肌痛症的女性中，抑郁和焦虑是否与疲劳、睡眠障碍、疼痛灾难化、运动恐惧和疼痛严重程度存在差异关联。对经皮神经电刺激纤维肌痛症活动研究的基线数据进行了分析。在 191 名参与者中，50%报告存在高焦虑和/或抑郁（17%高焦虑，9%高抑郁，24%两者均有）。疲劳和睡眠障碍与高抑郁相关（ < 0.05）。疼痛严重程度、疼痛灾难化和运动恐惧与高焦虑和高抑郁相关（ < 0.05）。讨论了潜在机制的可能影响以及对靶向治疗的需求。
