Emerg Infect Dis. 2018 Jan;24(1):178-80. doi: 10.3201/eid2401.171605. Epub 2018 Jan 17.
We report partial molecular characterization of isolates from an autochthonous chikungunya virus cluster in Latium Region. E1 sequences from 3 patients differ substantially from sequences from the 2007 outbreak in Italy and lack the A226V substitution associated with increased viral fitness in the Aedes albopictus mosquito vector.
我们报告了拉齐奥地区地方性基孔肯雅病毒群的分离株的部分分子特征。3 位患者的 E1 序列与意大利 2007 年暴发的序列有很大差异,且缺乏与在白纹伊蚊媒介中增加病毒适应性相关的 A226V 取代。