Pereira Henrique Marcelo Gualberto, Sardela Vinicius Figueiredo, Padilha Monica Costa, Mirotti Luciana, Casilli Alessandro, de Oliveira Fabio Azamor, de Albuquerque Cavalcanti Gustavo, Rodrigues Lucas Martins Lisandro, de Araujo Amanda Lessa Dutra, Levy Rachel Santos, Teixeira Pedro Antonio Castelo, de Oliveira Felipe Alves Gomes, Duarte Ana Carolina Giordani, Carneiro Ana Carolina Dudenhoeffer, Evaristo Joseph Albert Medeiros, Dos Santos Gustavo Ramalho Cardoso, da Costa Giovanni Carlo Verissimo, de Lima Castro Fernando, Nogueira Fabio Cesar Sousa, Scalco Fernanda Bertão, Pizzatti Luciana, de Aquino Neto Francisco Radler
Federal University of Rio de Janeiro - UFRJ, Brazilian Doping Control Laboratory - LBCD, LADETEC, Av. Horácio Macedo, 1281 - Polo de Química - Bloco C - Cidade Universitária - Ιlha do Fundão - Rio de Janeiro, Brazil.
Federal University of Rio de Janeiro - UFRJ, Laboratório de Biologia Molecular e Proteômica do Sangue - LABMOPS, LADETEC, Av. Horácio Macedo, 1281 - Polo de Química - Bloco C - Cidade Universitária - Ιlha do Fundão - Rio de Janeiro, Brazil.
Drug Test Anal. 2017 Nov;9(11-12):1658-1672. doi: 10.1002/dta.2329. Epub 2017 Nov 16.
This paper summarises the results obtained from the doping control analyses performed during the Summer XXXI Olympic Games (August 3-21, 2016) and the XV Paralympic Games (September 7-18, 2016). The analyses of all doping control samples were performed at the Brazilian Doping Control Laboratory (LBCD), a World Anti-Doping Agency (WADA)-accredited laboratory located in Rio de Janeiro, Brazil. A new facility at Rio de Janeiro Federal University (UFRJ) was built and fully operated by over 700 professionals, including Brazilian and international scientists, administrative staff, and volunteers. For the Olympic Games, 4913 samples were analysed. In 29 specimens, the presence of a prohibited substance was confirmed, resulting in adverse analytical findings (AAFs). For the Paralympic Games, 1687 samples were analysed, 12 of which were reported as AAFs. For both events, 82.8% of the samples were urine, and 17.2% were blood samples. In total, more than 31 000 analytical procedures were conducted. New WADA technical documents were fully implemented; consequently, state-of-the-art analytical toxicology instrumentation and strategies were applied during the Games, including different types of mass spectrometry (MS) analysers, peptide, and protein detection strategies, endogenous steroid profile measurements, and blood analysis. This enormous investment yielded one of the largest Olympic legacies in Brazil and South America. Copyright © 2017 John Wiley & Sons, Ltd.
本文总结了在第三十一届夏季奥运会（2016年8月3日至21日）和第十五届残奥会（2016年9月7日至18日）期间进行的兴奋剂检测分析结果。所有兴奋剂检测样本的分析均在巴西兴奋剂检测实验室（LBCD）进行，该实验室是一家位于巴西里约热内卢的世界反兴奋剂机构（WADA）认可实验室。里约热内卢联邦大学（UFRJ）新建了一个设施，由700多名专业人员全面运营，其中包括巴西和国际科学家、行政人员及志愿者。奥运会期间，共分析了4913个样本。在29个样本中，确认存在违禁物质，导致出现不利分析结果（AAFs）。残奥会期间，共分析了1687个样本，其中12个被报告为AAFs。两项赛事中，82.8%的样本为尿液，17.2%为血液样本。总共进行了超过31000次分析程序。WADA的新技术文件得到全面实施；因此，奥运会期间应用了最先进的分析毒理学仪器和策略，包括不同类型的质谱（MS）分析仪、肽和蛋白质检测策略、内源性类固醇谱测量以及血液分析。这项巨大的投入成为了巴西和南美洲最大的奥运遗产之一。版权所有© 2017约翰·威利父子有限公司。
