Xu Yanggui, Li Adela Jing, Li Kaibin, Qin Junhao, Li Huashou
College of Natural Resources and Environment, South China Agricultural University, Guangzhou, 510642, China; Guangdong Engineering Research Center for Modern Eco-agriculture and Circular Agriculture/Key Laboratory of Agroecology and Rural Environment of Guangzhou Regular Higher Education Institutions, Guangzhou, 510642, China.
College of Natural Resources and Environment, South China Agricultural University, Guangzhou, 510642, China; Guangdong Engineering Research Center for Modern Eco-agriculture and Circular Agriculture/Key Laboratory of Agroecology and Rural Environment of Guangzhou Regular Higher Education Institutions, Guangzhou, 510642, China.
Aquat Toxicol. 2017 Dec;193:136-143. doi: 10.1016/j.aquatox.2017.10.011. Epub 2017 Oct 17.
This study tests the hypotheses that whether environmental relevance of glyphosate would help control spread of the invasive snail Pomacea canaliculata, or benefit its population growth worldwide. Our results showed that glyphosate induced acute toxicity to the snail only at high concentrations (96h LC50 at 175mg/L) unlikely to occur in the environment. Long-term exposures to glyphosate at sublethal levels (20 and 120mg/L) caused inhibition of food intake, limitation of growth performance and alterations in metabolic profiles of the snail. It is worth noting that glyphosate at 2mg/L benefited growth performance in P. canaliculata. Chronic exposures of glyphosate significantly enhanced overall metabolic rate and altered catabolism from protein to carbohydrate/lipid mode. Cellular responses in enzyme activities showed that the exposed snails could increase tolerance by their defense system against glyphosate-induced oxidative stress, and adjustment of metabolism to mitigate energy crisis. Our study displayed that sublethal concentrations of glyphosate might be helpful in control of the invasive species by food intake, growth performance and metabolic interruption; whether environmental relevance of glyphosate (≤2mg/L) benefits population growth of P. canaliculata is still inconclusive, which requires further field study.
草甘膦与环境的相关性是否有助于控制入侵螺福寿螺的扩散，或者是否有利于其在全球范围内的种群增长。我们的结果表明，草甘膦仅在高浓度（96小时半数致死浓度为175毫克/升）时才会对福寿螺产生急性毒性，而这种高浓度在环境中不太可能出现。在亚致死水平（20和120毫克/升）下长期接触草甘膦会导致福寿螺的食物摄入量受到抑制、生长性能受限以及代谢谱发生改变。值得注意的是，2毫克/升的草甘膦对福寿螺的生长性能有促进作用。长期接触草甘膦会显著提高整体代谢率，并使分解代谢从蛋白质模式转变为碳水化合物/脂质模式。酶活性方面的细胞反应表明，接触草甘膦的福寿螺可以通过其防御系统提高对草甘膦诱导的氧化应激的耐受性，并通过调整代谢来缓解能量危机。我们的研究表明，亚致死浓度的草甘膦可能通过影响食物摄入量、生长性能和代谢来帮助控制入侵物种；草甘膦（≤2毫克/升）与环境的相关性是否有利于福寿螺种群增长仍无定论，这需要进一步的实地研究。
