Suppr超能文献

留置胸膜导管治疗肺陷闭患者恶性胸腔积液:如何进行

Management of malignant pleural effusions in patients with trapped lung with indwelling pleural catheter: how to do it.

作者信息

Bertolaccini Luca, Viti Andrea, Terzi Alberto

机构信息

Thoracic Surgery Unit, Sacro Cuore Don Calabria Research Hospital, Cancer Care Center, Negrar Verona, Italy.

出版信息

J Vis Surg. 2016 Mar 11;2:44. doi: 10.21037/jovs.2016.02.06. eCollection 2016.

Abstract

Malignant pleural effusion (MPE) is a well-known sign of an end-stage cancer and affects the quality of life of these patients. The primary goal in the management of MPE should be a soothing treatment with the palliation of symptoms. Pleurodesis may be accomplished with chemical irritation of the pleura and represents the commonest treatment of MPE with palliative intent. Pleurodesis may be achieved through a chest drainage placement or a video-assisted thoracic surgery (VATS) procedure. The uniportal VATS talc poudrage is considered the gold standard of care for fit patients, while talc slurry (through the chest drainage) is reserved to those patients with important comorbidities not tolerating a surgical procedure. However, if the lung remains trapped after fluid evacuation or if the daily fluid output after chest tube insertion is major than 300 mL/day, the talc pleurodesis is likely to fail. Therefore, in those patients who are unfit for pleurodesis (low performance status or comorbidity), or with a recurrent MPE after chemical pleurodesis, or with trapped lung, the outpatient intermittent drainage through a subcutaneous tunnelled indwelling pleural catheter (IPC) effectively relieved dyspnoea without complications. The treatment of recurrent MPE with an IPC reduces symptoms and improves quality of life in patients with end-stage cancers. The complication rate is low; therefore, the IPC can be easily managed at home. The IPC is safe, easy to place and effective for the palliation of MPE. It could help the clinical need of the thoracic surgeons and the other members of a multidisciplinary cancer team.

摘要

恶性胸腔积液(MPE)是终末期癌症的一个众所周知的体征,会影响这些患者的生活质量。MPE治疗的主要目标应该是进行舒缓治疗以缓解症状。胸膜固定术可通过胸膜化学刺激来完成,是MPE最常见的姑息性治疗方法。胸膜固定术可通过胸腔引流置管或电视辅助胸腔镜手术(VATS)来实现。单孔VATS滑石粉喷洒术被认为是适合患者的护理金标准,而滑石粉悬液(通过胸腔引流)则适用于那些有严重合并症而无法耐受手术的患者。然而,如果液体排出后肺仍被包裹,或者胸腔置管后每日液体引流量大于300 mL/天,滑石粉胸膜固定术很可能会失败。因此,对于那些不适合进行胸膜固定术(低体能状态或合并症)、化学性胸膜固定术后MPE复发或有肺包裹的患者,通过皮下隧道留置胸膜导管(IPC)进行门诊间歇性引流可有效缓解呼吸困难且无并发症。用IPC治疗复发性MPE可减轻终末期癌症患者的症状并提高其生活质量。并发症发生率低;因此,IPC在家中易于管理。IPC安全、易于放置且对MPE的姑息治疗有效。它有助于满足胸外科医生和多学科癌症团队其他成员的临床需求。

相似文献

9
Postoperative outcome after palliative treatment of malignant pleural effusion.恶性胸腔积液姑息性治疗后的术后结果。
Thorac Cancer. 2022 Aug;13(15):2158-2163. doi: 10.1111/1759-7714.14534. Epub 2022 Jun 15.
10
[Chinese expert consensus on treatment of malignant pleural effusion (2023 Edition)].《恶性胸腔积液治疗中国专家共识(2023年版)》
Zhonghua Jie He He Hu Xi Za Zhi. 2023 Dec 12;46(12):1189-1203. doi: 10.3760/cma.j.cn112147-20230902-00126.

本文引用的文献

3
Current controversies in the management of malignant pleural effusions.恶性胸腔积液管理中的当前争议
Semin Respir Crit Care Med. 2014 Dec;35(6):723-31. doi: 10.1055/s-0034-1395795. Epub 2014 Dec 2.
6
Malignant pleural effusion and algorithm management.恶性胸腔积液及诊疗策略
J Thorac Dis. 2013 Sep;5 Suppl 4(Suppl 4):S413-9. doi: 10.3978/j.issn.2072-1439.2013.09.04.
9
Tunneled pleural catheters: an update for 2013.经皮胸膜腔导管:2013 年更新
Clin Chest Med. 2013 Mar;34(1):73-80. doi: 10.1016/j.ccm.2012.12.003.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验