Xue Liang, Pang Xuguang, Zhang Yongxing, Ding Jianyong
Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
J Vis Surg. 2017 Jun 16;3:83. doi: 10.21037/jovs.2017.05.04. eCollection 2017.
Video-assisted thoracoscopic surgery (VATS) in thymectomy has shown safe and effective with many advantages in myasthenia gravis (MG) patients with or without thymoma than transsternal approach. This video aims to show the procedure of extended thymectomy via a cervical incision additional to bilateral VATS approach in a MG patient with an early stage thymoma.
The patient was a 46-year-old male who had onset of symptoms of blurred vision, dysarthria and dysphagia for 10 months before administration. A diagnosis of MG was then confirmed using anticholinesterase test and electromyography test by neurologists. A CT scan showed enlarged thymus and a mass close to the left innominate vein in the anterior mediastinum with a size of 12 mm × 13 mm. Without any contradictions, the patient was planned to receive a procedure of extended thymectomy.
The patient recovered with no complications and was discharged on the 8th postoperative day. Histological pathology examination revealed a type B3 thymoma of Masaoka stage II.
Oncological principles and immunological considerations are equally important in surgery for the MG patients with thymoma. All the thymus gland in the mediastinum including ectopic thymic tissue in the cervical region should be removed in the procedure. In conclusion, we suggest this approach to be safe and feasible for thymoma surgery in patients with MG.
对于重症肌无力(MG)患者,无论有无胸腺瘤,电视辅助胸腔镜手术(VATS)下胸腺切除术已显示出安全有效,相较于经胸骨入路具有诸多优势。本视频旨在展示在一名早期胸腺瘤的MG患者中,通过双侧VATS入路并附加颈部切口进行扩大胸腺切除术的手术过程。
患者为一名46岁男性,在就诊前10个月出现视力模糊、构音障碍和吞咽困难症状。随后神经科医生通过抗胆碱酯酶试验和肌电图检查确诊为MG。CT扫描显示胸腺增大,前纵隔靠近左无名静脉处有一大小为12mm×13mm的肿块。在无任何禁忌证的情况下,计划对该患者进行扩大胸腺切除术。
患者恢复良好,无并发症,术后第8天出院。组织病理学检查显示为Masaoka II期B3型胸腺瘤。
对于有胸腺瘤的MG患者,肿瘤学原则和免疫学考量在手术中同样重要。手术过程中应切除纵隔内所有胸腺组织,包括颈部区域的异位胸腺组织。总之,我们认为这种方法对于MG患者的胸腺瘤手术是安全可行的。