White Lindsey, Ybarra Michael
Department of Emergency Medicine, Washington Hospital Center, 110 Irving Street Northwest, Suite NA 1177, Washington, DC 20010, USA.
Department of Emergency Medicine, MedStar Georgetown University Hospital, Washington, DC, USA.
Hematol Oncol Clin North Am. 2017 Dec;31(6):981-993. doi: 10.1016/j.hoc.2017.08.004.
Fever is a common presenting complaint among adult or pediatric patients in the emergency department setting. Although fever in healthy individuals does not necessarily indicate severe illness, fever in patients with neutropenia may herald a life-threatening infection. Therefore, prompt recognition of patients with neutropenic fever is imperative. Serious bacterial illness is a significant cause of morbidity and mortality for neutropenic patients. Neutropenic fever should trigger the initiation of a rapid work-up and the administration of empiric systemic antibiotic therapy to attenuate or avoid the progression along the spectrum of sepsis, severe sepsis, septic shock syndrome, and death.
发热是急诊科成年或儿科患者常见的就诊主诉。虽然健康个体发热不一定表明患有严重疾病，但中性粒细胞减少症患者发热可能预示着危及生命的感染。因此，及时识别中性粒细胞减少性发热患者至关重要。严重细菌感染是中性粒细胞减少症患者发病和死亡的重要原因。中性粒细胞减少性发热应促使迅速进行检查并给予经验性全身抗生素治疗，以减轻或避免沿着脓毒症、严重脓毒症、感染性休克综合征及死亡的病程进展。
