Young Janet S, Simmons Jennifer W
Department of Emergency Medicine, Virginia Tech-Carilion School of Medicine, Carilion Clinic, 1906 Belleview Avenue, Roanoke, VA 24014, USA.
Department of Pediatrics, Children's Hospital of The King's Daughters, 601 Childrens Lane, Norfolk, VA 23507, USA.
Hematol Oncol Clin North Am. 2017 Dec;31(6):995-1010. doi: 10.1016/j.hoc.2017.08.005.
Patients with complications of chemotherapy, either acute or chronic, are frequently encountered in the emergency department (ED). Some patients present with complaints immediately after chemotherapy administration, whereas others may show subtle, secondary signs or may have no signs or symptoms of chemotoxicity. An increased index of suspicion prompts early recognition, diagnosis, and prevention of further iatrogenic injury. This article reviews characteristic hypersensitivity reactions, typical organ system dysfunction, and treatment strategies for adult patients who present to the ED with complications after chemotherapy.
化疗并发症患者，无论是急性还是慢性，在急诊科（ED）都很常见。一些患者在化疗给药后立即出现不适，而另一些患者可能表现出细微的继发症状，或者可能没有化学毒性的体征或症状。提高怀疑指数有助于早期识别、诊断和预防进一步的医源性损伤。本文综述了成年患者化疗后出现并发症并到急诊科就诊时的特征性过敏反应、典型器官系统功能障碍及治疗策略。
