Department of Infectious Diseases, Sapporo City General Hospital, 13 Chome 1-1, Kita 11 Jonishi, Chuo-ku, Sapporo, Hokkaido 060-8604, Japan.
Division of Geriatric Medicine, Department of Medicine, University of Pittsburgh, 3471 Fifth Avenue, Kaufmann Building Suite 500, Pittsburgh, PA 15213, USA.
Infect Dis Clin North Am. 2017 Dec;31(4):767-790. doi: 10.1016/j.idc.2017.07.006.
Respiratory viral infections may cause serious complications for older adults, including residents of long-term care facilities (LTCFs). Although influenza is the most common cause of viral respiratory infections among older adults, several other respiratory viruses also cause significant morbidity and mortality, most notably respiratory syncytial virus. Other noninfluenza respiratory viral pathogens include human metapneumovirus, parainfluenza virus, rhinovirus, coronavirus, and adenovirus. All of these may cause outbreaks among LTCF residents. Recently developed rapid diagnostic molecular tests may clarify the epidemiology of these viruses and have potential, through early identification, to limit the severity of outbreaks among older adults living in LTCFs.
呼吸道病毒感染可导致老年人发生严重并发症,包括长期护理机构(LTCF)中的居民。流感是老年人中最常见的病毒性呼吸道感染病因,但也有其他几种呼吸道病毒可导致较高的发病率和死亡率,其中最主要的是呼吸道合胞病毒。其他非流感呼吸道病毒病原体包括人偏肺病毒、副流感病毒、鼻病毒、冠状病毒和腺病毒。所有这些病毒都可能在 LTCF 居民中引起暴发。最近开发的快速诊断分子检测方法可能阐明这些病毒的流行病学特征,通过早期识别,有可能降低 LTCF 中老年人感染暴发的严重程度。